Kensler TW - Search Results

1

Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.

Yates MS, Tauchi M, Katsuoka F, Flanders KC, Liby KT, Honda T, Gribble GW, Johnson DA, Johnson JA, Burton NC, Guilarte TR, Yamamoto M, Sporn MB, Kensler TW. Yates MS, et al. Among authors: kensler tw. Mol Cancer Ther. 2007 Jan;6(1):154-62. doi: 10.1158/1535-7163.MCT-06-0516. Mol Cancer Ther. 2007. PMID: 17237276

2

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.

Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW. Ramos-Gomez M, et al. Among authors: kensler tw. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3410-5. doi: 10.1073/pnas.051618798. Proc Natl Acad Sci U S A. 2001. PMID: 11248092 Free PMC article.

3

Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.

Kwak MK, Itoh K, Yamamoto M, Sutter TR, Kensler TW. Kwak MK, et al. Among authors: kensler tw. Mol Med. 2001 Feb;7(2):135-45. Mol Med. 2001. PMID: 11471548 Free PMC article.

4

Role of phase 2 enzyme induction in chemoprotection by dithiolethiones.

Kwak MK, Egner PA, Dolan PM, Ramos-Gomez M, Groopman JD, Itoh K, Yamamoto M, Kensler TW. Kwak MK, et al. Among authors: kensler tw. Mutat Res. 2001 Sep 1;480-481:305-15. doi: 10.1016/s0027-5107(01)00190-7. Mutat Res. 2001. PMID: 11506823 Review.

5

Role of NRF2 in protection against hyperoxic lung injury in mice.

Cho HY, Jedlicka AE, Reddy SP, Kensler TW, Yamamoto M, Zhang LY, Kleeberger SR. Cho HY, et al. Among authors: kensler tw. Am J Respir Cell Mol Biol. 2002 Feb;26(2):175-82. doi: 10.1165/ajrcmb.26.2.4501. Am J Respir Cell Mol Biol. 2002. PMID: 11804867

6

Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter.

Kwak MK, Itoh K, Yamamoto M, Kensler TW. Kwak MK, et al. Among authors: kensler tw. Mol Cell Biol. 2002 May;22(9):2883-92. doi: 10.1128/MCB.22.9.2883-2892.2002. Mol Cell Biol. 2002. PMID: 11940647 Free PMC article.

7

Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.

Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M, Biswal S. Thimmulappa RK, et al. Among authors: kensler tw. Cancer Res. 2002 Sep 15;62(18):5196-203. Cancer Res. 2002. PMID: 12234984

8

Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.

Kwak MK, Wakabayashi N, Itoh K, Motohashi H, Yamamoto M, Kensler TW. Kwak MK, et al. Among authors: kensler tw. J Biol Chem. 2003 Mar 7;278(10):8135-45. doi: 10.1074/jbc.M211898200. Epub 2002 Dec 27. J Biol Chem. 2003. PMID: 12506115 Free article.

9

Interactive effects of nrf2 genotype and oltipraz on benzo[a]pyrene-DNA adducts and tumor yield in mice.

Ramos-Gomez M, Dolan PM, Itoh K, Yamamoto M, Kensler TW. Ramos-Gomez M, et al. Among authors: kensler tw. Carcinogenesis. 2003 Mar;24(3):461-7. doi: 10.1093/carcin/24.3.461. Carcinogenesis. 2003. PMID: 12663505

10

Induction of phase 2 enzymes by serum oxidized polyamines through activation of Nrf2: effect of the polyamine metabolite acrolein.

Kwak MK, Kensler TW, Casero RA Jr. Kwak MK, et al. Among authors: kensler tw. Biochem Biophys Res Commun. 2003 Jun 6;305(3):662-70. doi: 10.1016/s0006-291x(03)00834-9. Biochem Biophys Res Commun. 2003. PMID: 12763045

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