Liby KT - Search Results

1

Pharmacodynamic characterization of chemopreventive triterpenoids as exceptionally potent inducers of Nrf2-regulated genes.

Yates MS, Tauchi M, Katsuoka F, Flanders KC, Liby KT, Honda T, Gribble GW, Johnson DA, Johnson JA, Burton NC, Guilarte TR, Yamamoto M, Sporn MB, Kensler TW. Yates MS, et al. Among authors: liby kt. Mol Cancer Ther. 2007 Jan;6(1):154-62. doi: 10.1158/1535-7163.MCT-06-0516. Mol Cancer Ther. 2007. PMID: 17237276

2

The Multi-Faceted Consequences of NRF2 Activation throughout Carcinogenesis.

Occhiuto CJ, Moerland JA, Leal AS, Gallo KA, Liby KT. Occhiuto CJ, et al. Among authors: liby kt. Mol Cells. 2023 Mar 31;46(3):176-186. doi: 10.14348/molcells.2023.2191. Epub 2023 Mar 22. Mol Cells. 2023. PMID: 36994476 Free PMC article. Review.

3

The selective estrogen receptor modulator arzoxifene and the rexinoid LG100268 cooperate to promote transforming growth factor beta-dependent apoptosis in breast cancer.

Rendi MH, Suh N, Lamph WW, Krajewski S, Reed JC, Heyman RA, Berchuck A, Liby K, Risingsong R, Royce DB, Williams CR, Sporn MB. Rendi MH, et al. Cancer Res. 2004 May 15;64(10):3566-71. doi: 10.1158/0008-5472.CAN-04-0234. Cancer Res. 2004. PMID: 15150113

4

Design, synthesis, and biological evaluation of biotin conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid for the isolation of the protein targets.

Honda T, Janosik T, Honda Y, Han J, Liby KT, Williams CR, Couch RD, Anderson AC, Sporn MB, Gribble GW. Honda T, et al. Among authors: liby kt. J Med Chem. 2004 Sep 23;47(20):4923-32. doi: 10.1021/jm049727e. J Med Chem. 2004. PMID: 15369396

5

Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress.

Dinkova-Kostova AT, Liby KT, Stephenson KK, Holtzclaw WD, Gao X, Suh N, Williams C, Risingsong R, Honda T, Gribble GW, Sporn MB, Talalay P. Dinkova-Kostova AT, et al. Among authors: liby kt. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4584-9. doi: 10.1073/pnas.0500815102. Epub 2005 Mar 14. Proc Natl Acad Sci U S A. 2005. PMID: 15767573 Free PMC article.

6

The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling.

Liby K, Hock T, Yore MM, Suh N, Place AE, Risingsong R, Williams CR, Royce DB, Honda T, Honda Y, Gribble GW, Hill-Kapturczak N, Agarwal A, Sporn MB. Liby K, et al. Cancer Res. 2005 Jun 1;65(11):4789-98. doi: 10.1158/0008-5472.CAN-04-4539. Cancer Res. 2005. PMID: 15930299

7

Cancer chemoprevention: scientific promise, clinical uncertainty.

Sporn MB, Liby KT. Sporn MB, et al. Among authors: liby kt. Nat Clin Pract Oncol. 2005 Oct;2(10):518-25. doi: 10.1038/ncponc0319. Nat Clin Pract Oncol. 2005. PMID: 16205771 Review.

8

Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.

Yates MS, Kwak MK, Egner PA, Groopman JD, Bodreddigari S, Sutter TR, Baumgartner KJ, Roebuck BD, Liby KT, Yore MM, Honda T, Gribble GW, Sporn MB, Kensler TW. Yates MS, et al. Among authors: liby kt. Cancer Res. 2006 Feb 15;66(4):2488-94. doi: 10.1158/0008-5472.CAN-05-3823. Cancer Res. 2006. PMID: 16489057

9

The synthetic triterpenoid CDDO-imidazolide induces monocytic differentiation by activating the Smad and ERK signaling pathways in HL60 leukemia cells.

Ji Y, Lee HJ, Goodman C, Uskokovic M, Liby K, Sporn M, Suh N. Ji Y, et al. Mol Cancer Ther. 2006 Jun;5(6):1452-8. doi: 10.1158/1535-7163.MCT-06-0136. Mol Cancer Ther. 2006. PMID: 16818503

10

The synthetic triterpenoid CDDO-Imidazolide suppresses STAT phosphorylation and induces apoptosis in myeloma and lung cancer cells.

Liby K, Voong N, Williams CR, Risingsong R, Royce DB, Honda T, Gribble GW, Sporn MB, Letterio JJ. Liby K, et al. Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4288-93. doi: 10.1158/1078-0432.CCR-06-0215. Clin Cancer Res. 2006. PMID: 16857804

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