Hong Z - Search Results

1

Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase.

Cheney IW, Yan S, Appleby T, Walker H, Vo T, Yao N, Hamatake R, Hong Z, Wu JZ. Cheney IW, et al. Among authors: hong z. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1679-83. doi: 10.1016/j.bmcl.2006.12.086. Epub 2007 Jan 4. Bioorg Med Chem Lett. 2007. PMID: 17251021

2

Structure of human uridine-cytidine kinase 2 determined by SIRAS using a rotating-anode X-ray generator and a single samarium derivative.

Appleby TC, Larson G, Cheney IW, Walker H, Wu JZ, Zhong W, Hong Z, Yao N. Appleby TC, et al. Among authors: hong z. Acta Crystallogr D Biol Crystallogr. 2005 Mar;61(Pt 3):278-84. doi: 10.1107/S0907444904032937. Epub 2005 Feb 24. Acta Crystallogr D Biol Crystallogr. 2005. PMID: 15735337

3

Recent advances in discovery and development of promising therapeutics against hepatitis C virus NS5B RNA-dependent RNA polymerase.

Wu JZ, Yao N, Walker M, Hong Z. Wu JZ, et al. Among authors: hong z. Mini Rev Med Chem. 2005 Dec;5(12):1103-12. doi: 10.2174/138955705774933310. Mini Rev Med Chem. 2005. PMID: 16375756 Review.

4

Discovery of 3-hydroxy-4-carboxyalkylamidino-5-arylamino-isothiazoles as potent MEK1 inhibitors.

Varaprasad CV, Barawkar D, El Abdellaoui H, Chakravarty S, Allan M, Chen H, Zhang W, Wu JZ, Tam R, Hamatake R, Lang S, Hong Z. Varaprasad CV, et al. Among authors: hong z. Bioorg Med Chem Lett. 2006 Aug 1;16(15):3975-80. doi: 10.1016/j.bmcl.2006.05.019. Epub 2006 May 24. Bioorg Med Chem Lett. 2006. PMID: 16725322

5

Tri-substituted triazoles as potent non-nucleoside inhibitors of the HIV-1 reverse transcriptase.

De La Rosa M, Kim HW, Gunic E, Jenket C, Boyle U, Koh YH, Korboukh I, Allan M, Zhang W, Chen H, Xu W, Nilar S, Yao N, Hamatake R, Lang SA, Hong Z, Zhang Z, Girardet JL. De La Rosa M, et al. Among authors: hong z. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4444-9. doi: 10.1016/j.bmcl.2006.06.048. Epub 2006 Jun 27. Bioorg Med Chem Lett. 2006. PMID: 16806925

6

Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors.

Yan S, Appleby T, Larson G, Wu JZ, Hamatake R, Hong Z, Yao N. Yan S, et al. Among authors: hong z. Bioorg Med Chem Lett. 2006 Nov 15;16(22):5888-91. doi: 10.1016/j.bmcl.2006.08.056. Epub 2006 Aug 24. Bioorg Med Chem Lett. 2006. PMID: 16934455

7

Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors.

El Abdellaoui H, Varaprasad CV, Barawkar D, Chakravarty S, Maderna A, Tam R, Chen H, Allan M, Wu JZ, Appleby T, Yan S, Zhang W, Lang S, Yao N, Hamatake R, Hong Z. El Abdellaoui H, et al. Among authors: hong z. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5561-6. doi: 10.1016/j.bmcl.2006.08.048. Epub 2006 Aug 24. Bioorg Med Chem Lett. 2006. PMID: 16934458

8

Identification of novel, selective and potent Chk2 inhibitors.

Larson G, Yan S, Chen H, Rong F, Hong Z, Wu JZ. Larson G, et al. Among authors: hong z. Bioorg Med Chem Lett. 2007 Jan 1;17(1):172-5. doi: 10.1016/j.bmcl.2006.09.067. Epub 2006 Oct 10. Bioorg Med Chem Lett. 2007. PMID: 17035018

9

Novel thiazolones as HCV NS5B polymerase allosteric inhibitors: Further designs, SAR, and X-ray complex structure.

Yan S, Larson G, Wu JZ, Appleby T, Ding Y, Hamatake R, Hong Z, Yao N. Yan S, et al. Among authors: hong z. Bioorg Med Chem Lett. 2007 Jan 1;17(1):63-7. doi: 10.1016/j.bmcl.2006.09.095. Epub 2006 Oct 4. Bioorg Med Chem Lett. 2007. PMID: 17049849

10

Isothiazoles as active-site inhibitors of HCV NS5B polymerase.

Yan S, Appleby T, Gunic E, Shim JH, Tasu T, Kim H, Rong F, Chen H, Hamatake R, Wu JZ, Hong Z, Yao N. Yan S, et al. Among authors: hong z. Bioorg Med Chem Lett. 2007 Jan 1;17(1):28-33. doi: 10.1016/j.bmcl.2006.10.002. Epub 2006 Oct 5. Bioorg Med Chem Lett. 2007. PMID: 17049853

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