Heverin M - Search Results

1

Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid.

Meaney S, Heverin M, Panzenboeck U, Ekström L, Axelsson M, Andersson U, Diczfalusy U, Pikuleva I, Wahren J, Sattler W, Björkhem I. Meaney S, et al. Among authors: heverin m. J Lipid Res. 2007 Apr;48(4):944-51. doi: 10.1194/jlr.M600529-JLR200. Epub 2007 Jan 24. J Lipid Res. 2007. PMID: 17251592 Free article.

2

Oxysterols and Alzheimer's disease.

Björkhem I, Heverin M, Leoni V, Meaney S, Diczfalusy U. Björkhem I, et al. Among authors: heverin m. Acta Neurol Scand Suppl. 2006;185:43-9. doi: 10.1111/j.1600-0404.2006.00684.x. Acta Neurol Scand Suppl. 2006. PMID: 16866910 Review.

3

Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease.

Heverin M, Bogdanovic N, Lütjohann D, Bayer T, Pikuleva I, Bretillon L, Diczfalusy U, Winblad B, Björkhem I. Heverin M, et al. J Lipid Res. 2004 Jan;45(1):186-93. doi: 10.1194/jlr.M300320-JLR200. Epub 2003 Oct 1. J Lipid Res. 2004. PMID: 14523054 Free article.

4

Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain.

Heverin M, Meaney S, Lütjohann D, Diczfalusy U, Wahren J, Björkhem I. Heverin M, et al. J Lipid Res. 2005 May;46(5):1047-52. doi: 10.1194/jlr.M500024-JLR200. Epub 2005 Mar 1. J Lipid Res. 2005. PMID: 15741649 Free article.

5

On the regulatory role of side-chain hydroxylated oxysterols in the brain. Lessons from CYP27A1 transgenic and Cyp27a1(-/-) mice.

Ali Z, Heverin M, Olin M, Acimovic J, Lövgren-Sandblom A, Shafaati M, Båvner A, Meiner V, Leitersdorf E, Björkhem I. Ali Z, et al. Among authors: heverin m. J Lipid Res. 2013 Apr;54(4):1033-43. doi: 10.1194/jlr.M034124. Epub 2013 Jan 2. J Lipid Res. 2013. PMID: 23284090 Free PMC article.

6

Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1): marked insensitivity toward different regulatory axes.

Ohyama Y, Meaney S, Heverin M, Ekström L, Brafman A, Shafir M, Andersson U, Olin M, Eggertsen G, Diczfalusy U, Feinstein E, Björkhem I. Ohyama Y, et al. Among authors: heverin m. J Biol Chem. 2006 Feb 17;281(7):3810-20. doi: 10.1074/jbc.M505179200. Epub 2005 Nov 30. J Biol Chem. 2006. PMID: 16321981 Free article.

7

Novel LC-MS/MS method for assay of 7alpha-hydroxy-4-cholesten-3-one in human plasma. Evidence for a significant extrahepatic metabolism.

Lövgren-Sandblom A, Heverin M, Larsson H, Lundström E, Wahren J, Diczfalusy U, Björkhem I. Lövgren-Sandblom A, et al. Among authors: heverin m. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 1;856(1-2):15-9. doi: 10.1016/j.jchromb.2007.05.019. Epub 2007 May 29. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17561450

8

Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol.

Heverin M, Meaney S, Brafman A, Shafir M, Olin M, Shafaati M, von Bahr S, Larsson L, Lövgren-Sandblom A, Diczfalusy U, Parini P, Feinstein E, Björkhem I. Heverin M, et al. Arterioscler Thromb Vasc Biol. 2007 Oct;27(10):2191-7. doi: 10.1161/ATVBAHA.107.149823. Epub 2007 Aug 30. Arterioscler Thromb Vasc Biol. 2007. PMID: 17761942

9

Side chain-oxidized oxysterols regulate the brain renin-angiotensin system through a liver X receptor-dependent mechanism.

Mateos L, Ismail MA, Gil-Bea FJ, Schüle R, Schöls L, Heverin M, Folkesson R, Björkhem I, Cedazo-Mínguez A. Mateos L, et al. Among authors: heverin m. J Biol Chem. 2011 Jul 22;286(29):25574-85. doi: 10.1074/jbc.M111.236877. Epub 2011 May 31. J Biol Chem. 2011. PMID: 21628469 Free PMC article.

10

Sulphatation does not appear to be a protective mechanism to prevent oxysterol accumulation in humans and mice.

Acimovic J, Lövgren-Sandblom A, Olin M, Ali Z, Heverin M, Schüle R, Schöls L, Fischler B, Fickert P, Trauner M, Björkhem I. Acimovic J, et al. Among authors: heverin m. PLoS One. 2013 Jul 3;8(7):e68031. doi: 10.1371/journal.pone.0068031. Print 2013. PLoS One. 2013. PMID: 23844150 Free PMC article.

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