Spletstoser JT - Search Results

1

Synthesis of docetaxel and butitaxel analogues through kinetic resolution of racemic beta-lactams with 7-O-triethylsilylbaccatin III.

Ge H, Spletstoser JT, Yang Y, Kayser M, Georg GI. Ge H, et al. Among authors: spletstoser jt. J Org Chem. 2007 Feb 2;72(3):756-9. doi: 10.1021/jo061339s. J Org Chem. 2007. PMID: 17253791 Free PMC article.

2

Synthesis and anti-tubulin activity of a 3'-(4-azidophenyl)-3'-dephenylpaclitaxel photoaffinity probe.

Spletstoser JT, Flaherty PT, Himes RH, Georg GI. Spletstoser JT, et al. J Med Chem. 2004 Dec 16;47(26):6459-65. doi: 10.1021/jm030581d. J Med Chem. 2004. PMID: 15588080

3

Single-site chemical modification at C10 of the baccatin III core of paclitaxel and Taxol C reduces P-glycoprotein interactions in bovine brain microvessel endothelial cells.

Spletstoser JT, Turunen BJ, Desino K, Rice A, Datta A, Dutta D, Huff JK, Himes RH, Audus KL, Seelig A, Georg GI. Spletstoser JT, et al. Bioorg Med Chem Lett. 2006 Feb;16(3):495-8. doi: 10.1016/j.bmcl.2005.10.063. Epub 2005 Nov 10. Bioorg Med Chem Lett. 2006. PMID: 16289636

4

Mild and selective hydrozirconation of amides to aldehydes using Cp2Zr(H)Cl: scope and mechanistic insight.

Spletstoser JT, White JM, Tunoori AR, Georg GI. Spletstoser JT, et al. J Am Chem Soc. 2007 Mar 21;129(11):3408-19. doi: 10.1021/ja066362+. Epub 2007 Feb 22. J Am Chem Soc. 2007. PMID: 17315870 Free PMC article.

5

Synthesis of oximidine II by a copper-mediated reductive ene-yne macrocyclization.

Schneider CM, Khownium K, Li W, Spletstoser JT, Haack T, Georg GI. Schneider CM, et al. Among authors: spletstoser jt. Angew Chem Int Ed Engl. 2011 Aug 16;50(34):7855-7. doi: 10.1002/anie.201103081. Epub 2011 Jun 29. Angew Chem Int Ed Engl. 2011. PMID: 21717556 Free PMC article.

6

Tandem silylformylation-crotylsilylation/Tamao oxidation of internal alkynes: a remarkable example of generating complexity from simplicity.

Spletstoser JT, Zacuto MJ, Leighton JL. Spletstoser JT, et al. Org Lett. 2008 Dec 18;10(24):5593-6. doi: 10.1021/ol802489w. Org Lett. 2008. PMID: 19007175 Free PMC article.

7

Discovery of piperazic acid peptide deformylase inhibitors with in vivo activity for respiratory tract and skin infections.

Spletstoser JT, Dreabit J, Knox AN, Benowitz A, Campobasso N, Ward P, Cui G, Lewandowski T, McCloskey L, Aubart KM. Spletstoser JT, et al. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2410-2414. doi: 10.1016/j.bmcl.2019.05.028. Epub 2019 May 16. Bioorg Med Chem Lett. 2019. PMID: 31160176

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