Gassner NC - Search Results

1

Pyrroloacridine alkaloids from Plakortis quasiamphiaster: structures and bioactivity.

Ralifo P, Sanchez L, Gassner NC, Tenney K, Lokey RS, Holman TR, Valeriote FA, Crews P. Ralifo P, et al. Among authors: gassner nc. J Nat Prod. 2007 Jan;70(1):95-9. doi: 10.1021/np060585w. J Nat Prod. 2007. PMID: 17253856 Free PMC article.

2

Accelerating the discovery of biologically active small molecules using a high-throughput yeast halo assay.

Gassner NC, Tamble CM, Bock JE, Cotton N, White KN, Tenney K, St Onge RP, Proctor MJ, Giaever G, Nislow C, Davis RW, Crews P, Holman TR, Lokey RS. Gassner NC, et al. J Nat Prod. 2007 Mar;70(3):383-90. doi: 10.1021/np060555t. Epub 2007 Feb 10. J Nat Prod. 2007. PMID: 17291044 Free PMC article.

3

Pinpointing pseurotins from a marine-derived Aspergillus as tools for chemical genetics using a synthetic lethality yeast screen.

Boot CM, Gassner NC, Compton JE, Tenney K, Tamble CM, Lokey RS, Holman TR, Crews P. Boot CM, et al. Among authors: gassner nc. J Nat Prod. 2007 Oct;70(10):1672-5. doi: 10.1021/np070307c. Epub 2007 Oct 12. J Nat Prod. 2007. PMID: 17929896

4

A beta-carboline alkaloid from the Papua New Guinea marine sponge hyrtios reticulatus.

Inman WD, Bray WM, Gassner NC, Lokey RS, Tenney K, Shen YY, Tendyke K, Suh T, Crews P. Inman WD, et al. Among authors: gassner nc. J Nat Prod. 2010 Feb 26;73(2):255-7. doi: 10.1021/np9005426. J Nat Prod. 2010. PMID: 20000782 Free PMC article.

5

New structures and bioactivity properties of jasplakinolide (jaspamide) analogues from marine sponges.

Robinson SJ, Morinaka BI, Amagata T, Tenney K, Bray WM, Gassner NC, Lokey RS, Crews P. Robinson SJ, et al. Among authors: gassner nc. J Med Chem. 2010 Feb 25;53(4):1651-61. doi: 10.1021/jm9013554. J Med Chem. 2010. PMID: 20121114 Free PMC article.

6

Biostructural features of additional jasplakinolide (jaspamide) analogues.

Watts KR, Morinaka BI, Amagata T, Robinson SJ, Tenney K, Bray WM, Gassner NC, Lokey RS, Media J, Valeriote FA, Crews P. Watts KR, et al. Among authors: gassner nc. J Nat Prod. 2011 Mar 25;74(3):341-51. doi: 10.1021/np100721g. Epub 2011 Jan 11. J Nat Prod. 2011. PMID: 21241058 Free PMC article.

7

Natural product libraries to accelerate the high-throughput discovery of therapeutic leads.

Johnson TA, Sohn J, Inman WD, Estee SA, Loveridge ST, Vervoort HC, Tenney K, Liu J, Ang KK, Ratnam J, Bray WM, Gassner NC, Shen YY, Lokey RS, McKerrow JH, Boundy-Mills K, Nukanto A, Kanti A, Julistiono H, Kardono LB, Bjeldanes LF, Crews P. Johnson TA, et al. Among authors: gassner nc. J Nat Prod. 2011 Dec 27;74(12):2545-55. doi: 10.1021/np200673b. Epub 2011 Nov 30. J Nat Prod. 2011. PMID: 22129061 Free PMC article.

8

Discovery of platelet-type 12-human lipoxygenase selective inhibitors by high-throughput screening of structurally diverse libraries.

Deschamps JD, Gautschi JT, Whitman S, Johnson TA, Gassner NC, Crews P, Holman TR. Deschamps JD, et al. Among authors: gassner nc. Bioorg Med Chem. 2007 Nov 15;15(22):6900-8. doi: 10.1016/j.bmc.2007.08.015. Epub 2007 Aug 22. Bioorg Med Chem. 2007. PMID: 17826100 Free PMC article.

9

An image-based 384-well high-throughput screening method for the discovery of biofilm inhibitors in Vibrio cholerae.

Peach KC, Bray WM, Shikuma NJ, Gassner NC, Lokey RS, Yildiz FH, Linington RG. Peach KC, et al. Among authors: gassner nc. Mol Biosyst. 2011 Apr;7(4):1176-84. doi: 10.1039/c0mb00276c. Epub 2011 Jan 18. Mol Biosyst. 2011. PMID: 21246108 Free PMC article.

10

Cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action.

Kapitzky L, Beltrao P, Berens TJ, Gassner N, Zhou C, Wüster A, Wu J, Babu MM, Elledge SJ, Toczyski D, Lokey RS, Krogan NJ. Kapitzky L, et al. Mol Syst Biol. 2010 Dec 21;6:451. doi: 10.1038/msb.2010.107. Mol Syst Biol. 2010. PMID: 21179023 Free PMC article.

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