Tothova Z - Search Results

1

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.

Tothova Z, Kollipara R, Huntly BJ, Lee BH, Castrillon DH, Cullen DE, McDowell EP, Lazo-Kallanian S, Williams IR, Sears C, Armstrong SA, Passegué E, DePinho RA, Gilliland DG. Tothova Z, et al. Cell. 2007 Jan 26;128(2):325-39. doi: 10.1016/j.cell.2007.01.003. Cell. 2007. PMID: 17254970 Free article.

2

NPM-ALK fusion kinase of anaplastic large-cell lymphoma regulates survival and proliferative signaling through modulation of FOXO3a.

Gu TL, Tothova Z, Scheijen B, Griffin JD, Gilliland DG, Sternberg DW. Gu TL, et al. Among authors: tothova z. Blood. 2004 Jun 15;103(12):4622-9. doi: 10.1182/blood-2003-03-0820. Epub 2004 Feb 12. Blood. 2004. PMID: 14962911 Free article.

3

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis.

Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, Miao L, Tothova Z, Horner JW, Carrasco DR, Jiang S, Gilliland DG, Chin L, Wong WH, Castrillon DH, DePinho RA. Paik JH, et al. Among authors: tothova z. Cell. 2007 Jan 26;128(2):309-23. doi: 10.1016/j.cell.2006.12.029. Cell. 2007. PMID: 17254969 Free PMC article.

4

The retinoblastoma binding protein RBP2 is an H3K4 demethylase.

Klose RJ, Yan Q, Tothova Z, Yamane K, Erdjument-Bromage H, Tempst P, Gilliland DG, Zhang Y, Kaelin WG Jr. Klose RJ, et al. Among authors: tothova z. Cell. 2007 Mar 9;128(5):889-900. doi: 10.1016/j.cell.2007.02.013. Epub 2007 Feb 22. Cell. 2007. PMID: 17320163 Free article.

5

FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia.

Lee BH, Tothova Z, Levine RL, Anderson K, Buza-Vidas N, Cullen DE, McDowell EP, Adelsperger J, Fröhling S, Huntly BJ, Beran M, Jacobsen SE, Gilliland DG. Lee BH, et al. Among authors: tothova z. Cancer Cell. 2007 Oct;12(4):367-80. doi: 10.1016/j.ccr.2007.08.031. Cancer Cell. 2007. PMID: 17936561 Free PMC article.

6

FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system.

Tothova Z, Gilliland DG. Tothova Z, et al. Cell Stem Cell. 2007 Aug 16;1(2):140-52. doi: 10.1016/j.stem.2007.07.017. Cell Stem Cell. 2007. PMID: 18371346 Free article. Review.

7

A radical bailout strategy for cancer stem cells.

Tothova Z, Gilliland DG. Tothova Z, et al. Cell Stem Cell. 2009 Mar 6;4(3):196-7. doi: 10.1016/j.stem.2009.02.008. Cell Stem Cell. 2009. PMID: 19265655 Free article.

8

mTOR activation induces tumor suppressors that inhibit leukemogenesis and deplete hematopoietic stem cells after Pten deletion.

Lee JY, Nakada D, Yilmaz OH, Tothova Z, Joseph NM, Lim MS, Gilliland DG, Morrison SJ. Lee JY, et al. Among authors: tothova z. Cell Stem Cell. 2010 Nov 5;7(5):593-605. doi: 10.1016/j.stem.2010.09.015. Cell Stem Cell. 2010. PMID: 21040901 Free PMC article.

9

Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification.

Cornejo MG, Mabialah V, Sykes SM, Khandan T, Lo Celso C, Lopez CK, Rivera-Muñoz P, Rameau P, Tothova Z, Aster JC, DePinho RA, Scadden DT, Gilliland DG, Mercher T. Cornejo MG, et al. Among authors: tothova z. Blood. 2011 Aug 4;118(5):1264-73. doi: 10.1182/blood-2011-01-328567. Epub 2011 Jun 7. Blood. 2011. PMID: 21653327 Free PMC article.

10

AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias.

Sykes SM, Lane SW, Bullinger L, Kalaitzidis D, Yusuf R, Saez B, Ferraro F, Mercier F, Singh H, Brumme KM, Acharya SS, Scholl C, Tothova Z, Attar EC, Fröhling S, DePinho RA, Armstrong SA, Gilliland DG, Scadden DT. Sykes SM, et al. Among authors: tothova z. Cell. 2011 Sep 2;146(5):697-708. doi: 10.1016/j.cell.2011.07.032. Cell. 2011. PMID: 21884932 Free PMC article.

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