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Page 1
Amelioration of progressive renal injury by genetic manipulation of Klotho gene.
Haruna Y, Kashihara N, Satoh M, Tomita N, Namikoshi T, Sasaki T, Fujimori T, Xie P, Kanwar YS. Haruna Y, et al. Among authors: fujimori t. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2331-6. doi: 10.1073/pnas.0611079104. Epub 2007 Feb 7. Proc Natl Acad Sci U S A. 2007. PMID: 17287345 Free PMC article.
Sinoatrial node dysfunction and early unexpected death of mice with a defect of klotho gene expression.
Takeshita K, Fujimori T, Kurotaki Y, Honjo H, Tsujikawa H, Yasui K, Lee JK, Kamiya K, Kitaichi K, Yamamoto K, Ito M, Kondo T, Iino S, Inden Y, Hirai M, Murohara T, Kodama I, Nabeshima Y. Takeshita K, et al. Among authors: fujimori t. Circulation. 2004 Apr 13;109(14):1776-82. doi: 10.1161/01.CIR.0000124224.48962.32. Epub 2004 Mar 22. Circulation. 2004. PMID: 15037532
Severely reduced production of klotho in human chronic renal failure kidney.
Koh N, Fujimori T, Nishiguchi S, Tamori A, Shiomi S, Nakatani T, Sugimura K, Kishimoto T, Kinoshita S, Kuroki T, Nabeshima Y. Koh N, et al. Among authors: fujimori t. Biochem Biophys Res Commun. 2001 Feb 2;280(4):1015-20. doi: 10.1006/bbrc.2000.4226. Biochem Biophys Res Commun. 2001. PMID: 11162628
Klotho protein deficiency leads to overactivation of mu-calpain.
Manya H, Inomata M, Fujimori T, Dohmae N, Sato Y, Takio K, Nabeshima Y, Endo T. Manya H, et al. Among authors: fujimori t. J Biol Chem. 2002 Sep 20;277(38):35503-8. doi: 10.1074/jbc.M206033200. Epub 2002 Jul 15. J Biol Chem. 2002. PMID: 12119304 Free article.
alpha-Klotho as a regulator of calcium homeostasis.
Imura A, Tsuji Y, Murata M, Maeda R, Kubota K, Iwano A, Obuse C, Togashi K, Tominaga M, Kita N, Tomiyama K, Iijima J, Nabeshima Y, Fujioka M, Asato R, Tanaka S, Kojima K, Ito J, Nozaki K, Hashimoto N, Ito T, Nishio T, Uchiyama T, Fujimori T, Nabeshima Y. Imura A, et al. Among authors: fujimori t. Science. 2007 Jun 15;316(5831):1615-8. doi: 10.1126/science.1135901. Science. 2007. PMID: 17569864
725 results