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Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice.
Grant AD, Cottrell GS, Amadesi S, Trevisani M, Nicoletti P, Materazzi S, Altier C, Cenac N, Zamponi GW, Bautista-Cruz F, Lopez CB, Joseph EK, Levine JD, Liedtke W, Vanner S, Vergnolle N, Geppetti P, Bunnett NW. Grant AD, et al. Among authors: bunnett nw. J Physiol. 2007 Feb 1;578(Pt 3):715-33. doi: 10.1113/jphysiol.2006.121111. Epub 2006 Nov 23. J Physiol. 2007. PMID: 17124270 Free PMC article.
Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia.
Sipe WE, Brierley SM, Martin CM, Phillis BD, Cruz FB, Grady EF, Liedtke W, Cohen DM, Vanner S, Blackshaw LA, Bunnett NW. Sipe WE, et al. Among authors: bunnett nw. Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1288-98. doi: 10.1152/ajpgi.00002.2008. Epub 2008 Mar 6. Am J Physiol Gastrointest Liver Physiol. 2008. PMID: 18325985 Free article.
Sensitization of peripheral sensory nerves by mediators from colonic biopsies of diarrhea-predominant irritable bowel syndrome patients: a role for PAR2.
Valdez-Morales EE, Overington J, Guerrero-Alba R, Ochoa-Cortes F, Ibeakanma CO, Spreadbury I, Bunnett NW, Beyak M, Vanner SJ. Valdez-Morales EE, et al. Among authors: bunnett nw. Am J Gastroenterol. 2013 Oct;108(10):1634-43. doi: 10.1038/ajg.2013.241. Epub 2013 Aug 20. Am J Gastroenterol. 2013. PMID: 23958521
338 results