Bernhard H - Search Results

1

Reversible HLA multimers (Streptamers) for the isolation of human cytotoxic T lymphocytes functionally active against tumor- and virus-derived antigens.

Neudorfer J, Schmidt B, Huster KM, Anderl F, Schiemann M, Holzapfel G, Schmidt T, Germeroth L, Wagner H, Peschel C, Busch DH, Bernhard H. Neudorfer J, et al. Among authors: bernhard h. J Immunol Methods. 2007 Mar 30;320(1-2):119-31. doi: 10.1016/j.jim.2007.01.001. Epub 2007 Jan 31. J Immunol Methods. 2007. PMID: 17306825

2

Isolation and expansion of tumor-reactive cytotoxic T-cell clones for adoptive immunotherapy.

Bernhard H, Schmidt B, Busch DH, Peschel C. Bernhard H, et al. Methods Mol Med. 2005;109:175-84. doi: 10.1385/1-59259-862-5:175. Methods Mol Med. 2005. PMID: 15585921

3

Allorestricted T lymphocytes with a high avidity T-cell receptor towards NY-ESO-1 have potent anti-tumor activity.

Krönig H, Hofer K, Conrad H, Guilaume P, Müller J, Schiemann M, Lennerz V, Cosma A, Peschel C, Busch DH, Romero P, Bernhard H. Krönig H, et al. Among authors: bernhard h. Int J Cancer. 2009 Aug 1;125(3):649-55. doi: 10.1002/ijc.24414. Int J Cancer. 2009. PMID: 19444908

4

CTLs directed against HER2 specifically cross-react with HER3 and HER4.

Conrad H, Gebhard K, Krönig H, Neudorfer J, Busch DH, Peschel C, Bernhard H. Conrad H, et al. Among authors: bernhard h. J Immunol. 2008 Jun 15;180(12):8135-45. doi: 10.4049/jimmunol.180.12.8135. J Immunol. 2008. PMID: 18523278

5

Melanoma-reactive class I-restricted cytotoxic T cell clones are stimulated by dendritic cells loaded with synthetic peptides, but fail to respond to dendritic cells pulsed with melanoma-derived heat shock proteins in vitro.

Fleischer K, Schmidt B, Kastenmüller W, Busch DH, Drexler I, Sutter G, Heike M, Peschel C, Bernhard H. Fleischer K, et al. Among authors: bernhard h. J Immunol. 2004 Jan 1;172(1):162-9. doi: 10.4049/jimmunol.172.1.162. J Immunol. 2004. PMID: 14688322

6

Antihuman epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab enhances cytolytic activity of class I-restricted HER2-specific T lymphocytes against HER2-overexpressing tumor cells.

zum Büschenfelde CM, Hermann C, Schmidt B, Peschel C, Bernhard H. zum Büschenfelde CM, et al. Among authors: bernhard h. Cancer Res. 2002 Apr 15;62(8):2244-7. Cancer Res. 2002. PMID: 11956077

7

Reversible MHC multimer staining for functional isolation of T-cell populations and effective adoptive transfer.

Knabel M, Franz TJ, Schiemann M, Wulf A, Villmow B, Schmidt B, Bernhard H, Wagner H, Busch DH. Knabel M, et al. Among authors: bernhard h. Nat Med. 2002 Jun;8(6):631-7. doi: 10.1038/nm0602-631. Nat Med. 2002. PMID: 12042816

8

The immunogenicity of Bcr-Abl expressing dendritic cells is dependent on the Bcr-Abl kinase activity and dominated by Bcr-Abl regulated antigens.

Scheich F, Duyster J, Peschel C, Bernhard H. Scheich F, et al. Among authors: bernhard h. Blood. 2007 Oct 1;110(7):2556-60. doi: 10.1182/blood-2007-01-071001. Epub 2007 Jun 19. Blood. 2007. PMID: 17579186 Free article.

9

Adoptive transfer of autologous, HER2-specific, cytotoxic T lymphocytes for the treatment of HER2-overexpressing breast cancer.

Bernhard H, Neudorfer J, Gebhard K, Conrad H, Hermann C, Nährig J, Fend F, Weber W, Busch DH, Peschel C. Bernhard H, et al. Cancer Immunol Immunother. 2008 Feb;57(2):271-80. doi: 10.1007/s00262-007-0355-7. Epub 2007 Jul 24. Cancer Immunol Immunother. 2008. PMID: 17646988 Free PMC article. Clinical Trial.

10

Generation of tumor-reactive CTL against the tumor-associated antigen HER2 using retrovirally transduced dendritic cells derived from CD34+ hemopoietic progenitor cells.

Meyer zum Büschenfelde C, Nicklisch N, Rose-John S, Peschel C, Bernhard H. Meyer zum Büschenfelde C, et al. Among authors: bernhard h. J Immunol. 2000 Oct 1;165(7):4133-40. doi: 10.4049/jimmunol.165.7.4133. J Immunol. 2000. PMID: 11034426

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