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Inhibition of p38 mitogen-activated protein kinase is effective in the treatment of experimental crescentic glomerulonephritis and suppresses monocyte chemoattractant protein-1 but not IL-1beta or IL-6.
J Am Soc Nephrol. 2007 Apr;18(4):1167-79. doi: 10.1681/ASN.2006010050. Epub 2007 Feb 21.
J Am Soc Nephrol. 2007.
PMID: 17314328
Treatment with a cyclin-dependent kinase inhibitor, seliciclib, is effective in reducing glomerular macrophage numbers and the severity of established experimental glomerulonephritis.
Sheryanna AM, Smith J, Bhangal G, Barnett A, McClue S, Tam FW, Cook T, Pusey CD.
Sheryanna AM, et al.
Nephrology (Carlton). 2011 May;16(4):410-6. doi: 10.1111/j.1440-1797.2010.01416.x.
Nephrology (Carlton). 2011.
PMID: 21518118
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