Sharma SV - Search Results

1

Epidermal growth factor receptor mutations in lung cancer.

Sharma SV, Bell DW, Settleman J, Haber DA. Sharma SV, et al. Nat Rev Cancer. 2007 Mar;7(3):169-81. doi: 10.1038/nrc2088. Nat Rev Cancer. 2007. PMID: 17318210 Review.

2

Molecular targeted therapy of lung cancer: EGFR mutations and response to EGFR inhibitors.

Haber DA, Bell DW, Sordella R, Kwak EL, Godin-Heymann N, Sharma SV, Lynch TJ, Settleman J. Haber DA, et al. Among authors: sharma sv. Cold Spring Harb Symp Quant Biol. 2005;70:419-26. doi: 10.1101/sqb.2005.70.043. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869779 Review.

3

Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib.

Kwak EL, Sordella R, Bell DW, Godin-Heymann N, Okimoto RA, Brannigan BW, Harris PL, Driscoll DR, Fidias P, Lynch TJ, Rabindran SK, McGinnis JP, Wissner A, Sharma SV, Isselbacher KJ, Settleman J, Haber DA. Kwak EL, et al. Among authors: sharma sv. Proc Natl Acad Sci U S A. 2005 May 24;102(21):7665-70. doi: 10.1073/pnas.0502860102. Epub 2005 May 16. Proc Natl Acad Sci U S A. 2005. PMID: 15897464 Free PMC article.

4

Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.

Bell DW, Gore I, Okimoto RA, Godin-Heymann N, Sordella R, Mulloy R, Sharma SV, Brannigan BW, Mohapatra G, Settleman J, Haber DA. Bell DW, et al. Among authors: sharma sv. Nat Genet. 2005 Dec;37(12):1315-6. doi: 10.1038/ng1671. Epub 2005 Oct 30. Nat Genet. 2005. PMID: 16258541

5

A common signaling cascade may underlie "addiction" to the Src, BCR-ABL, and EGF receptor oncogenes.

Sharma SV, Gajowniczek P, Way IP, Lee DY, Jiang J, Yuza Y, Classon M, Haber DA, Settleman J. Sharma SV, et al. Cancer Cell. 2006 Nov;10(5):425-35. doi: 10.1016/j.ccr.2006.09.014. Cancer Cell. 2006. PMID: 17097564 Free PMC article.

6

Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling.

McDermott U, Sharma SV, Dowell L, Greninger P, Montagut C, Lamb J, Archibald H, Raudales R, Tam A, Lee D, Rothenberg SM, Supko JG, Sordella R, Ulkus LE, Iafrate AJ, Maheswaran S, Njauw CN, Tsao H, Drew L, Hanke JH, Ma XJ, Erlander MG, Gray NS, Haber DA, Settleman J. McDermott U, et al. Among authors: sharma sv. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19936-41. doi: 10.1073/pnas.0707498104. Epub 2007 Dec 6. Proc Natl Acad Sci U S A. 2007. PMID: 18077425 Free PMC article.

7

Oncogene addiction: setting the stage for molecularly targeted cancer therapy.

Sharma SV, Settleman J. Sharma SV, et al. Genes Dev. 2007 Dec 15;21(24):3214-31. doi: 10.1101/gad.1609907. Genes Dev. 2007. PMID: 18079171 Free article. Review.

8

High-throughput lung cancer cell line screening for genotype-correlated sensitivity to an EGFR kinase inhibitor.

McDermott U, Sharma SV, Settleman J. McDermott U, et al. Among authors: sharma sv. Methods Enzymol. 2008;438:331-41. doi: 10.1016/S0076-6879(07)38023-3. Methods Enzymol. 2008. PMID: 18413259

9

Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma.

Montagut C, Sharma SV, Shioda T, McDermott U, Ulman M, Ulkus LE, Dias-Santagata D, Stubbs H, Lee DY, Singh A, Drew L, Haber DA, Settleman J. Montagut C, et al. Among authors: sharma sv. Cancer Res. 2008 Jun 15;68(12):4853-61. doi: 10.1158/0008-5472.CAN-07-6787. Cancer Res. 2008. PMID: 18559533 Free PMC article.

10

ErbBs in lung cancer.

Sharma SV, Settleman J. Sharma SV, et al. Exp Cell Res. 2009 Feb 15;315(4):557-71. doi: 10.1016/j.yexcr.2008.07.026. Epub 2008 Aug 6. Exp Cell Res. 2009. PMID: 18721806 Review.

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