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Page 1
Site-specific atherogenic gene expression correlates with subsequent variable lesion development in coronary and peripheral vasculature.
Mohler ER 3rd, Sarov-Blat L, Shi Y, Hamamdzic D, Zalewski A, Macphee C, Llano R, Pelchovitz D, Mainigi SK, Osman H, Hallman T, Steplewski K, Gertz Z, Lu MM, Wilensky RL. Mohler ER 3rd, et al. Among authors: steplewski k. Arterioscler Thromb Vasc Biol. 2008 May;28(5):850-5. doi: 10.1161/ATVBAHA.107.154534. Epub 2008 Feb 14. Arterioscler Thromb Vasc Biol. 2008. PMID: 18276914
PPARdelta activation normalizes cardiac substrate metabolism and reduces right ventricular hypertrophy in congestive heart failure.
Jucker BM, Doe CP, Schnackenberg CG, Olzinski AR, Maniscalco K, Williams C, Hu TC, Lenhard SC, Costell M, Bernard R, Sarov-Blat L, Steplewski K, Willette RN. Jucker BM, et al. Among authors: steplewski k. J Cardiovasc Pharmacol. 2007 Jul;50(1):25-34. doi: 10.1097/FJC.0b013e31804b4163. J Cardiovasc Pharmacol. 2007. PMID: 17666912
Quantitative analysis of orphan G protein-coupled receptor mRNAs by TaqMan Real-Time PCR: G2A and GPR4 lysophospholipid receptor expression in leukocytes and in a rat myocardial infarction-heart failure model.
Douglas SA, Ao Z, Johns DG, Maniscalco K, Willette RN, Sarov-Blat L, Cogswell JP, Seepersaud S, Murdock P, Steplewski KM, Patel L. Douglas SA, et al. Among authors: steplewski km. Methods Mol Biol. 2005;306:27-49. doi: 10.1385/1-59259-927-3:027. Methods Mol Biol. 2005. PMID: 15867463 No abstract available.
Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure.
Jaye MC, Krawiec JA, Campobasso N, Smallwood A, Qiu C, Lu Q, Kerrigan JJ, De Los Frailes Alvaro M, Laffitte B, Liu WS, Marino JP Jr, Meyer CR, Nichols JA, Parks DJ, Perez P, Sarov-Blat L, Seepersaud SD, Steplewski KM, Thompson SK, Wang P, Watson MA, Webb CL, Haigh D, Caravella JA, Macphee CH, Willson TM, Collins JL. Jaye MC, et al. Among authors: steplewski km. J Med Chem. 2005 Aug 25;48(17):5419-22. doi: 10.1021/jm050532w. J Med Chem. 2005. PMID: 16107141
AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1.
Muir AI, Chamberlain L, Elshourbagy NA, Michalovich D, Moore DJ, Calamari A, Szekeres PG, Sarau HM, Chambers JK, Murdock P, Steplewski K, Shabon U, Miller JE, Middleton SE, Darker JG, Larminie CG, Wilson S, Bergsma DJ, Emson P, Faull R, Philpott KL, Harrison DC. Muir AI, et al. Among authors: steplewski k. J Biol Chem. 2001 Aug 3;276(31):28969-75. doi: 10.1074/jbc.M102743200. Epub 2001 May 31. J Biol Chem. 2001. PMID: 11387329 Free article.
The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids.
Brown AJ, Goldsworthy SM, Barnes AA, Eilert MM, Tcheang L, Daniels D, Muir AI, Wigglesworth MJ, Kinghorn I, Fraser NJ, Pike NB, Strum JC, Steplewski KM, Murdock PR, Holder JC, Marshall FH, Szekeres PG, Wilson S, Ignar DM, Foord SM, Wise A, Dowell SJ. Brown AJ, et al. J Biol Chem. 2003 Mar 28;278(13):11312-9. doi: 10.1074/jbc.M211609200. Epub 2002 Dec 19. J Biol Chem. 2003. PMID: 12496283 Free article.
Molecular identification of high and low affinity receptors for nicotinic acid.
Wise A, Foord SM, Fraser NJ, Barnes AA, Elshourbagy N, Eilert M, Ignar DM, Murdock PR, Steplewski K, Green A, Brown AJ, Dowell SJ, Szekeres PG, Hassall DG, Marshall FH, Wilson S, Pike NB. Wise A, et al. Among authors: steplewski k. J Biol Chem. 2003 Mar 14;278(11):9869-74. doi: 10.1074/jbc.M210695200. Epub 2003 Jan 9. J Biol Chem. 2003. PMID: 12522134 Free article.
22 results