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Antitumor activity and novel DNA-self-strand-breaking mechanism of CNDAC (1-(2-C-cyano-2-deoxy-beta-D-arabino-pentofuranosyl) cytosine) and its N4-palmitoyl derivative (CS-682).
Hanaoka K, Suzuki M, Kobayashi T, Tanzawa F, Tanaka K, Shibayama T, Miura S, Ikeda T, Iwabuchi H, Nakagawa A, Mitsuhashi Y, Hisaoka M, Kaneko M, Tomida A, Wataya Y, Nomura T, Sasaki T, Matsuda A, Tsuruo T, Kurakata S. Hanaoka K, et al. Among authors: shibayama t. Int J Cancer. 1999 Jul 19;82(2):226-36. doi: 10.1002/(sici)1097-0215(19990719)82:2<226::aid-ijc13>3.0.co;2-x. Int J Cancer. 1999. PMID: 10389757
In vitro and in vivo antibacterial activities of CS-023 (RO4908463), a novel parenteral carbapenem.
Koga T, Abe T, Inoue H, Takenouchi T, Kitayama A, Yoshida T, Masuda N, Sugihara C, Kakuta M, Nakagawa M, Shibayama T, Matsushita Y, Hirota T, Ohya S, Utsui Y, Fukuoka T, Kuwahara S. Koga T, et al. Among authors: shibayama t. Antimicrob Agents Chemother. 2005 Aug;49(8):3239-50. doi: 10.1128/AAC.49.8.3239-3250.2005. Antimicrob Agents Chemother. 2005. PMID: 16048932 Free PMC article.
CYP2C8-Mediated Formation of a Human Disproportionate Metabolite of the Selective NaV1.7 Inhibitor DS-1971a, a Mixed Cytochrome P450 and Aldehyde Oxidase Substrate.
Asano D, Hamaue S, Zahir H, Shiozawa H, Nishiya Y, Kimura T, Kazui M, Yamamura N, Ikeguchi M, Shibayama T, Inoue SI, Shinozuka T, Watanabe T, Yahara C, Watanabe N, Yoshinari K. Asano D, et al. Among authors: shibayama t. Drug Metab Dispos. 2022 Mar;50(3):235-242. doi: 10.1124/dmd.121.000665. Epub 2021 Dec 20. Drug Metab Dispos. 2022. PMID: 34930785
360 results