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Codon conservation in the influenza A virus genome defines RNA packaging signals.
Gog JR, Afonso Edos S, Dalton RM, Leclercq I, Tiley L, Elton D, von Kirchbach JC, Naffakh N, Escriou N, Digard P. Gog JR, et al. Among authors: naffakh n. Nucleic Acids Res. 2007;35(6):1897-907. doi: 10.1093/nar/gkm087. Epub 2007 Mar 1. Nucleic Acids Res. 2007. PMID: 17332012 Free PMC article.
Multivalent Dynamic Colocalization of Avian Influenza Polymerase and Nucleoprotein by Intrinsically Disordered ANP32A Reveals the Molecular Basis of Human Adaptation.
Camacho-Zarco AR, Yu L, Krischuns T, Dedeoglu S, Maurin D, Bouvignies G, Crépin T, Ruigrok RWH, Cusack S, Naffakh N, Blackledge M. Camacho-Zarco AR, et al. Among authors: naffakh n. J Am Chem Soc. 2023 Sep 27;145(38):20985-21001. doi: 10.1021/jacs.3c06965. Epub 2023 Sep 14. J Am Chem Soc. 2023. PMID: 37707433 Free PMC article.
A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors.
Chen KY, Krischuns T, Ortega Varga L, Harigua-Souiai E, Paisant S, Zettor A, Chiaravalli J, Courtney D, O'Brien A, Baker SC, Isel C, Agou F, Jacob Y, Blondel A, Naffakh N. Chen KY, et al. Among authors: naffakh n. bioRxiv [Preprint]. 2021 Dec 21:2021.12.18.473303. doi: 10.1101/2021.12.18.473303. bioRxiv. 2021. Update in: Antiviral Res. 2022 May;201:105272. doi: 10.1016/j.antiviral.2022.105272 PMID: 34981051 Free PMC article. Updated. Preprint.
Design and synthesis of naturally-inspired SARS-CoV-2 inhibitors.
Hassan H, Chiavaralli J, Hassan A, Bedda L, Krischuns T, Chen KY, Li ASM, Delpal A, Decroly E, Vedadi M, Naffakh N, Agou F, Mallart S, Arafa RK, Arimondo PB. Hassan H, et al. Among authors: naffakh n. RSC Med Chem. 2023 Jan 25;14(3):507-519. doi: 10.1039/d2md00149g. eCollection 2023 Mar 22. RSC Med Chem. 2023. PMID: 36970153 Free PMC article.
Recombinant influenza A viruses harboring optimized dicistronic NA segment with an extended native 5' terminal sequence: induction of heterospecific B and T cell responses in mice.
Vieira Machado A, Naffakh N, Gerbaud S, van der Werf S, Escriou N. Vieira Machado A, et al. Among authors: naffakh n. Virology. 2006 Feb 5;345(1):73-87. doi: 10.1016/j.virol.2005.09.050. Epub 2005 Nov 3. Virology. 2006. PMID: 16271378 Free article.
We generated novel recombinant influenza A viruses (vNA38) harboring dicistronic NA segments with an extended native 5' terminal sequence of 70 nucleotides comprised of the last 42 nucleotides of the NA ORF and the 5' noncoding region (5' NCR). vNA38 viruses replicated stably and …
We generated novel recombinant influenza A viruses (vNA38) harboring dicistronic NA segments with an extended native 5' terminal sequence of …
92 results