Feldmann G - Search Results

1

Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers.

Feldmann G, Dhara S, Fendrich V, Bedja D, Beaty R, Mullendore M, Karikari C, Alvarez H, Iacobuzio-Donahue C, Jimeno A, Gabrielson KL, Matsui W, Maitra A. Feldmann G, et al. Cancer Res. 2007 Mar 1;67(5):2187-96. doi: 10.1158/0008-5472.CAN-06-3281. Cancer Res. 2007. PMID: 17332349 Free PMC article.

2

Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer.

Feldmann G, Habbe N, Dhara S, Bisht S, Alvarez H, Fendrich V, Beaty R, Mullendore M, Karikari C, Bardeesy N, Ouellette MM, Yu W, Maitra A. Feldmann G, et al. Gut. 2008 Oct;57(10):1420-30. doi: 10.1136/gut.2007.148189. Epub 2008 May 30. Gut. 2008. PMID: 18515410 Free PMC article.

3

Epidermal growth factor receptor and hedgehog signaling pathways are active in esophageal cancer cells from rat reflux model.

Sui G, Bonde P, Dhara S, Broor A, Wang J, Marti G, Feldmann G, Duncan M, Montgomery E, Maitra A, Harmon JW. Sui G, et al. Among authors: feldmann g. J Surg Res. 2006 Jul;134(1):1-9. doi: 10.1016/j.jss.2005.12.029. Epub 2006 Feb 20. J Surg Res. 2006. PMID: 16488438

4

Targeting the apoptotic machinery in pancreatic cancers using small-molecule antagonists of the X-linked inhibitor of apoptosis protein.

Karikari CA, Roy I, Tryggestad E, Feldmann G, Pinilla C, Welsh K, Reed JC, Armour EP, Wong J, Herman J, Rakheja D, Maitra A. Karikari CA, et al. Among authors: feldmann g. Mol Cancer Ther. 2007 Mar;6(3):957-66. doi: 10.1158/1535-7163.MCT-06-0634. Epub 2007 Mar 5. Mol Cancer Ther. 2007. PMID: 17339366 Free PMC article.

5

Mitochondrial DNA mutations in pancreatic cancer.

Kassauei K, Habbe N, Mullendore ME, Karikari CA, Maitra A, Feldmann G. Kassauei K, et al. Among authors: feldmann g. Int J Gastrointest Cancer. 2006;37(2-3):57-64. doi: 10.1007/s12029-007-0008-2. Int J Gastrointest Cancer. 2006. PMID: 17827523

6

Snail and Sonic Hedgehog activation in neuroendocrine tumors of the ileum.

Fendrich V, Waldmann J, Esni F, Ramaswamy A, Mullendore M, Buchholz M, Maitra A, Feldmann G. Fendrich V, et al. Among authors: feldmann g. Endocr Relat Cancer. 2007 Sep;14(3):865-74. doi: 10.1677/ERC-07-0108. Endocr Relat Cancer. 2007. PMID: 17914115

7

An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer.

Feldmann G, Fendrich V, McGovern K, Bedja D, Bisht S, Alvarez H, Koorstra JB, Habbe N, Karikari C, Mullendore M, Gabrielson KL, Sharma R, Matsui W, Maitra A. Feldmann G, et al. Mol Cancer Ther. 2008 Sep;7(9):2725-35. doi: 10.1158/1535-7163.MCT-08-0573. Mol Cancer Ther. 2008. PMID: 18790753 Free PMC article.

8

A direct pancreatic cancer xenograft model as a platform for cancer stem cell therapeutic development.

Jimeno A, Feldmann G, Suárez-Gauthier A, Rasheed Z, Solomon A, Zou GM, Rubio-Viqueira B, García-García E, López-Ríos F, Matsui W, Maitra A, Hidalgo M. Jimeno A, et al. Among authors: feldmann g. Mol Cancer Ther. 2009 Feb;8(2):310-4. doi: 10.1158/1535-7163.MCT-08-0924. Epub 2009 Jan 27. Mol Cancer Ther. 2009. PMID: 19174553 Free PMC article.

9

The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target.

Koorstra JB, Karikari CA, Feldmann G, Bisht S, Rojas PL, Offerhaus GJ, Alvarez H, Maitra A. Koorstra JB, et al. Among authors: feldmann g. Cancer Biol Ther. 2009 Apr;8(7):618-26. doi: 10.4161/cbt.8.7.7923. Epub 2009 Apr 22. Cancer Biol Ther. 2009. PMID: 19252414 Free PMC article.

10

Ligand-dependent Notch signaling is involved in tumor initiation and tumor maintenance in pancreatic cancer.

Mullendore ME, Koorstra JB, Li YM, Offerhaus GJ, Fan X, Henderson CM, Matsui W, Eberhart CG, Maitra A, Feldmann G. Mullendore ME, et al. Among authors: feldmann g. Clin Cancer Res. 2009 Apr 1;15(7):2291-301. doi: 10.1158/1078-0432.CCR-08-2004. Epub 2009 Mar 3. Clin Cancer Res. 2009. PMID: 19258443 Free PMC article.

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