Fisher LM - Search Results

1

Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target.

Laponogov I, Veselkov DA, Sohi MK, Pan XS, Achari A, Yang C, Ferrara JD, Fisher LM, Sanderson MR. Laponogov I, et al. Among authors: fisher lm. PLoS One. 2007 Mar 21;2(3):e301. doi: 10.1371/journal.pone.0000301. PLoS One. 2007. PMID: 17375187 Free PMC article.

2

Cloning and characterization of the parC and parE genes of Streptococcus pneumoniae encoding DNA topoisomerase IV: role in fluoroquinolone resistance.

Pan XS, Fisher LM. Pan XS, et al. Among authors: fisher lm. J Bacteriol. 1996 Jul;178(14):4060-9. doi: 10.1128/jb.178.14.4060-4069.1996. J Bacteriol. 1996. PMID: 8763932 Free PMC article.

3

Involvement of topoisomerase IV and DNA gyrase as ciprofloxacin targets in Streptococcus pneumoniae.

Pan XS, Ambler J, Mehtar S, Fisher LM. Pan XS, et al. Among authors: fisher lm. Antimicrob Agents Chemother. 1996 Oct;40(10):2321-6. doi: 10.1128/AAC.40.10.2321. Antimicrob Agents Chemother. 1996. PMID: 8891138 Free PMC article.

4

Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: selective targeting of gyrase or topoisomerase IV by quinolones.

Pan XS, Fisher LM. Pan XS, et al. Among authors: fisher lm. Antimicrob Agents Chemother. 1997 Feb;41(2):471-4. doi: 10.1128/AAC.41.2.471. Antimicrob Agents Chemother. 1997. PMID: 9021211 Free PMC article.

5

DNA gyrase and topoisomerase IV are dual targets of clinafloxacin action in Streptococcus pneumoniae.

Pan XS, Fisher LM. Pan XS, et al. Among authors: fisher lm. Antimicrob Agents Chemother. 1998 Nov;42(11):2810-6. doi: 10.1128/AAC.42.11.2810. Antimicrob Agents Chemother. 1998. PMID: 9797208 Free PMC article.

6

Streptococcus pneumoniae DNA gyrase and topoisomerase IV: overexpression, purification, and differential inhibition by fluoroquinolones.

Pan XS, Fisher LM. Pan XS, et al. Among authors: fisher lm. Antimicrob Agents Chemother. 1999 May;43(5):1129-36. doi: 10.1128/AAC.43.5.1129. Antimicrob Agents Chemother. 1999. PMID: 10223925 Free PMC article.

7

Engineering the specificity of antibacterial fluoroquinolones: benzenesulfonamide modifications at C-7 of ciprofloxacin change its primary target in Streptococcus pneumoniae from topoisomerase IV to gyrase.

Alovero FL, Pan XS, Morris JE, Manzo RH, Fisher LM. Alovero FL, et al. Among authors: fisher lm. Antimicrob Agents Chemother. 2000 Feb;44(2):320-5. doi: 10.1128/AAC.44.2.320-325.2000. Antimicrob Agents Chemother. 2000. PMID: 10639357 Free PMC article.

8

Potent antipneumococcal activity of gemifloxacin is associated with dual targeting of gyrase and topoisomerase IV, an in vivo target preference for gyrase, and enhanced stabilization of cleavable complexes in vitro.

Heaton VJ, Ambler JE, Fisher LM. Heaton VJ, et al. Among authors: fisher lm. Antimicrob Agents Chemother. 2000 Nov;44(11):3112-7. doi: 10.1128/AAC.44.11.3112-3117.2000. Antimicrob Agents Chemother. 2000. PMID: 11036032 Free PMC article.

9

Quinolone resistance mutations in Streptococcus pneumoniae GyrA and ParC proteins: mechanistic insights into quinolone action from enzymatic analysis, intracellular levels, and phenotypes of wild-type and mutant proteins.

Pan XS, Yague G, Fisher LM. Pan XS, et al. Among authors: fisher lm. Antimicrob Agents Chemother. 2001 Nov;45(11):3140-7. doi: 10.1128/AAC.45.11.3140-3147.2001. Antimicrob Agents Chemother. 2001. PMID: 11600369 Free PMC article.

10

Cleavable-complex formation by wild-type and quinolone-resistant Streptococcus pneumoniae type II topoisomerases mediated by gemifloxacin and other fluoroquinolones.

Yague G, Morris JE, Pan XS, Gould KA, Fisher LM. Yague G, et al. Among authors: fisher lm. Antimicrob Agents Chemother. 2002 Feb;46(2):413-9. doi: 10.1128/AAC.46.2.413-419.2002. Antimicrob Agents Chemother. 2002. PMID: 11796351 Free PMC article.

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