Sasai K - Search Results

1

Medulloblastomas derived from Cxcr6 mutant mice respond to treatment with a smoothened inhibitor.

Sasai K, Romer JT, Kimura H, Eberhart DE, Rice DS, Curran T. Sasai K, et al. Cancer Res. 2007 Apr 15;67(8):3871-7. doi: 10.1158/0008-5472.CAN-07-0493. Epub 2007 Apr 5. Cancer Res. 2007. PMID: 17413002

2

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

Romer JT, Kimura H, Magdaleno S, Sasai K, Fuller C, Baines H, Connelly M, Stewart CF, Gould S, Rubin LL, Curran T. Romer JT, et al. Among authors: sasai k. Cancer Cell. 2004 Sep;6(3):229-40. doi: 10.1016/j.ccr.2004.08.019. Cancer Cell. 2004. PMID: 15380514 Free article.

3

Shh pathway activity is down-regulated in cultured medulloblastoma cells: implications for preclinical studies.

Sasai K, Romer JT, Lee Y, Finkelstein D, Fuller C, McKinnon PJ, Curran T. Sasai K, et al. Cancer Res. 2006 Apr 15;66(8):4215-22. doi: 10.1158/0008-5472.CAN-05-4505. Cancer Res. 2006. PMID: 16618744

4

Loss of suppressor-of-fused function promotes tumorigenesis.

Lee Y, Kawagoe R, Sasai K, Li Y, Russell HR, Curran T, McKinnon PJ. Lee Y, et al. Among authors: sasai k. Oncogene. 2007 Sep 27;26(44):6442-7. doi: 10.1038/sj.onc.1210467. Epub 2007 Apr 23. Oncogene. 2007. PMID: 17452975

5

Oncogene-mediated human lung epithelial cell transformation produces adenocarcinoma phenotypes in vivo.

Sasai K, Sukezane T, Yanagita E, Nakagawa H, Hotta A, Itoh T, Akagi T. Sasai K, et al. Cancer Res. 2011 Apr 1;71(7):2541-9. doi: 10.1158/0008-5472.CAN-10-2221. Epub 2011 Mar 29. Cancer Res. 2011. PMID: 21447735

6

Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation.

Akagi T, Sasai K, Hanafusa H. Akagi T, et al. Among authors: sasai k. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13567-72. doi: 10.1073/pnas.1834876100. Epub 2003 Nov 3. Proc Natl Acad Sci U S A. 2003. PMID: 14597713 Free PMC article.

7

FRA1 is a determinant for the difference in RAS-induced transformation between human and rat fibroblasts.

Kakumoto K, Sasai K, Sukezane T, Oneyama C, Ishimaru S, Shibutani K, Mizushima H, Mekada E, Hanafusa H, Akagi T. Kakumoto K, et al. Among authors: sasai k. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5490-5. doi: 10.1073/pnas.0601222103. Epub 2006 Mar 28. Proc Natl Acad Sci U S A. 2006. PMID: 16569692 Free PMC article.

8

The Ras-MAPK pathway downregulates Caveolin-1 in rodent fibroblast but not in human fibroblasts: implications in the resistance to oncogene-mediated transformation.

Sasai K, Kakumoto K, Hanafusa H, Akagi T. Sasai K, et al. Oncogene. 2007 Jan 18;26(3):449-55. doi: 10.1038/sj.onc.1209792. Epub 2006 Jul 10. Oncogene. 2007. PMID: 16832346

9

O6-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies.

Sasai K, Akagi T, Aoyanagi E, Tabu K, Kaneko S, Tanaka S. Sasai K, et al. Mol Cancer. 2007 Jun 5;6:36. doi: 10.1186/1476-4598-6-36. Mol Cancer. 2007. PMID: 17547775 Free PMC article.

10

Establishment of a luciferase assay-based screening system: fumitremorgin C selectively inhibits cellular proliferation of immortalized astrocytes expressing an active form of AKT.

Wang L, Sasai K, Akagi T, Tanaka S. Wang L, et al. Among authors: sasai k. Biochem Biophys Res Commun. 2008 Aug 29;373(3):392-6. doi: 10.1016/j.bbrc.2008.06.032. Epub 2008 Jun 18. Biochem Biophys Res Commun. 2008. PMID: 18570889

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