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Page 1
Anxiolytic-like effects through a GLUK5 kainate receptor mechanism.
Alt A, Weiss B, Ornstein PL, Gleason SD, Bleakman D, Stratford RE Jr, Witkin JM. Alt A, et al. Among authors: witkin jm. Neuropharmacology. 2007 Jun;52(7):1482-7. doi: 10.1016/j.neuropharm.2007.02.005. Epub 2007 Mar 2. Neuropharmacology. 2007. PMID: 17418283
In vitro pharmacological and rat pharmacokinetic characterization of LY3020371, a potent and selective mGlu2/3 receptor antagonist.
Witkin JM, Ornstein PL, Mitch CH, Li R, Smith SC, Heinz BA, Wang XS, Xiang C, Carter JH, Anderson WH, Li X, Broad LM, Pasqui F, Fitzjohn SM, Sanger HE, Smith JL, Catlow J, Swanson S, Monn JA. Witkin JM, et al. Neuropharmacology. 2017 Mar 15;115:100-114. doi: 10.1016/j.neuropharm.2015.12.021. Epub 2015 Dec 31. Neuropharmacology. 2017. PMID: 26748052
AMPA receptor potentiators as novel antidepressants.
Alt A, Witkin JM, Bleakman D. Alt A, et al. Among authors: witkin jm. Curr Pharm Des. 2005;11(12):1511-27. doi: 10.2174/1381612053764814. Curr Pharm Des. 2005. PMID: 15892659 Review.
AMPA receptors in the therapeutic management of depression.
Bleakman D, Alt A, Witkin JM. Bleakman D, et al. Among authors: witkin jm. CNS Neurol Disord Drug Targets. 2007 Apr;6(2):117-26. doi: 10.2174/187152707780363258. CNS Neurol Disord Drug Targets. 2007. PMID: 17430149 Review.
A role for AMPA receptors in mood disorders.
Alt A, Nisenbaum ES, Bleakman D, Witkin JM. Alt A, et al. Among authors: witkin jm. Biochem Pharmacol. 2006 Apr 28;71(9):1273-88. doi: 10.1016/j.bcp.2005.12.022. Epub 2006 Jan 24. Biochem Pharmacol. 2006. PMID: 16442080 Review.
Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism.
Kato AS, Burris KD, Gardinier KM, Gernert DL, Porter WJ, Reel J, Ding C, Tu Y, Schober DA, Lee MR, Heinz BA, Fitch TE, Gleason SD, Catlow JT, Yu H, Fitzjohn SM, Pasqui F, Wang H, Qian Y, Sher E, Zwart R, Wafford KA, Rasmussen K, Ornstein PL, Isaac JT, Nisenbaum ES, Bredt DS, Witkin JM. Kato AS, et al. Among authors: witkin jm. Nat Med. 2016 Dec;22(12):1496-1501. doi: 10.1038/nm.4221. Epub 2016 Nov 7. Nat Med. 2016. PMID: 27820603
259 results