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Bone morphogenetic protein-2/4 signalling pathway components are expressed in the human thymus and inhibit early T-cell development.
Immunology. 2007 May;121(1):94-104. doi: 10.1111/j.1365-2567.2007.02541.x.
Immunology. 2007.
PMID: 17425602
Free PMC article.
Sonic hedgehog regulates early human thymocyte differentiation by counteracting the IL-7-induced development of CD34+ precursor cells.
Gutiérrez-Frías C, Sacedón R, Hernández-López C, Cejalvo T, Crompton T, Zapata AG, Varas A, Vicente A.
Gutiérrez-Frías C, et al.
J Immunol. 2004 Oct 15;173(8):5046-53. doi: 10.4049/jimmunol.173.8.5046.
J Immunol. 2004.
PMID: 15470048
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Sonic hedgehog is produced by follicular dendritic cells and protects germinal center B cells from apoptosis.
Sacedón R, Díez B, Nuñez V, Hernández-López C, Gutierrez-Frías C, Cejalvo T, Outram SV, Crompton T, Zapata AG, Vicente A, Varas A.
Sacedón R, et al. Among authors: gutierrez frias c.
J Immunol. 2005 Feb 1;174(3):1456-61. doi: 10.4049/jimmunol.174.3.1456.
J Immunol. 2005.
PMID: 15661904
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Survival and function of human thymic dendritic cells are dependent on autocrine Hedgehog signaling.
Varas A, Hernández-López C, Valencia J, Mattavelli S, Martínez VG, Hidalgo L, Gutiérrez-Frías C, Zapata AG, Sacedón R, Vicente A.
Varas A, et al. Among authors: gutierrez frias c.
J Leukoc Biol. 2008 Jun;83(6):1476-83. doi: 10.1189/jlb.1107792. Epub 2008 Mar 11.
J Leukoc Biol. 2008.
PMID: 18334540
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