Henkels KM - Search Results

1

Short-hairpin RNA-mediated stable silencing of Grb2 impairs cell growth and DNA synthesis.

Di Fulvio M, Henkels KM, Gomez-Cambronero J. Di Fulvio M, et al. Among authors: henkels km. Biochem Biophys Res Commun. 2007 Jun 8;357(3):737-42. doi: 10.1016/j.bbrc.2007.04.013. Epub 2007 Apr 10. Biochem Biophys Res Commun. 2007. PMID: 17445773 Free PMC article.

2

The Grb2/PLD2 interaction is essential for lipase activity, intracellular localization and signaling in response to EGF.

Di Fulvio M, Frondorf K, Henkels KM, Lehman N, Gomez-Cambronero J. Di Fulvio M, et al. Among authors: henkels km. J Mol Biol. 2007 Mar 30;367(3):814-24. doi: 10.1016/j.jmb.2007.01.021. Epub 2007 Jan 12. J Mol Biol. 2007. PMID: 17276458 Free PMC article.

3

PLD2 has both enzymatic and cell proliferation-inducing capabilities, that are differentially regulated by phosphorylation and dephosphorylation.

Henkels KM, Short S, Peng HJ, Di Fulvio M, Gomez-Cambronero J. Henkels KM, et al. Biochem Biophys Res Commun. 2009 Nov 13;389(2):224-8. doi: 10.1016/j.bbrc.2009.08.109. Epub 2009 Aug 26. Biochem Biophys Res Commun. 2009. PMID: 19715678 Free PMC article.

4

A comprehensive model that explains the regulation of phospholipase D2 activity by phosphorylation-dephosphorylation.

Henkels KM, Peng HJ, Frondorf K, Gomez-Cambronero J. Henkels KM, et al. Mol Cell Biol. 2010 May;30(9):2251-63. doi: 10.1128/MCB.01239-09. Epub 2010 Feb 22. Mol Cell Biol. 2010. PMID: 20176813 Free PMC article.

5

Phosphatidic acid is a leukocyte chemoattractant that acts through S6 kinase signaling.

Frondorf K, Henkels KM, Frohman MA, Gomez-Cambronero J. Frondorf K, et al. Among authors: henkels km. J Biol Chem. 2010 May 21;285(21):15837-47. doi: 10.1074/jbc.M109.070524. Epub 2010 Mar 19. J Biol Chem. 2010. PMID: 20304930 Free PMC article.

6

IL-8-induced neutrophil chemotaxis is mediated by Janus kinase 3 (JAK3).

Henkels KM, Frondorf K, Gonzalez-Mejia ME, Doseff AL, Gomez-Cambronero J. Henkels KM, et al. FEBS Lett. 2011 Jan 3;585(1):159-66. doi: 10.1016/j.febslet.2010.11.031. Epub 2010 Nov 21. FEBS Lett. 2011. PMID: 21095188 Free PMC article.

7

Evidence for two CRIB domains in phospholipase D2 (PLD2) that the enzyme uses to specifically bind to the small GTPase Rac2.

Peng HJ, Henkels KM, Mahankali M, Dinauer MC, Gomez-Cambronero J. Peng HJ, et al. Among authors: henkels km. J Biol Chem. 2011 May 6;286(18):16308-20. doi: 10.1074/jbc.M110.206672. Epub 2011 Mar 4. J Biol Chem. 2011. PMID: 21378159 Free PMC article.

8

Cell invasion of highly metastatic MTLn3 cancer cells is dependent on phospholipase D2 (PLD2) and Janus kinase 3 (JAK3).

Henkels KM, Farkaly T, Mahankali M, Segall JE, Gomez-Cambronero J. Henkels KM, et al. J Mol Biol. 2011 May 20;408(5):850-62. doi: 10.1016/j.jmb.2011.03.017. Epub 2011 Mar 22. J Mol Biol. 2011. PMID: 21414324 Free PMC article.

9

The dual effect of Rac2 on phospholipase D2 regulation that explains both the onset and termination of chemotaxis.

Peng HJ, Henkels KM, Mahankali M, Marchal C, Bubulya P, Dinauer MC, Gomez-Cambronero J. Peng HJ, et al. Among authors: henkels km. Mol Cell Biol. 2011 Jun;31(11):2227-40. doi: 10.1128/MCB.01348-10. Epub 2011 Mar 28. Mol Cell Biol. 2011. PMID: 21444720 Free PMC article.

10

A novel phospholipase D2-Grb2-WASp heterotrimer regulates leukocyte phagocytosis in a two-step mechanism.

Kantonen S, Hatton N, Mahankali M, Henkels KM, Park H, Cox D, Gomez-Cambronero J. Kantonen S, et al. Among authors: henkels km. Mol Cell Biol. 2011 Nov;31(22):4524-37. doi: 10.1128/MCB.05684-11. Epub 2011 Sep 19. Mol Cell Biol. 2011. PMID: 21930784 Free PMC article.

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