Bensch WR - Search Results

1

Secreted PCSK9 downregulates low density lipoprotein receptor through receptor-mediated endocytosis.

Qian YW, Schmidt RJ, Zhang Y, Chu S, Lin A, Wang H, Wang X, Beyer TP, Bensch WR, Li W, Ehsani ME, Lu D, Konrad RJ, Eacho PI, Moller DE, Karathanasis SK, Cao G. Qian YW, et al. Among authors: bensch wr. J Lipid Res. 2007 Jul;48(7):1488-98. doi: 10.1194/jlr.M700071-JLR200. Epub 2007 Apr 20. J Lipid Res. 2007. PMID: 17449864 Free article.

2

Secreted proprotein convertase subtilisin/kexin type 9 reduces both hepatic and extrahepatic low-density lipoprotein receptors in vivo.

Schmidt RJ, Beyer TP, Bensch WR, Qian YW, Lin A, Kowala M, Alborn WE, Konrad RJ, Cao G. Schmidt RJ, et al. Among authors: bensch wr. Biochem Biophys Res Commun. 2008 Jun 13;370(4):634-40. doi: 10.1016/j.bbrc.2008.04.004. Epub 2008 Apr 10. Biochem Biophys Res Commun. 2008. PMID: 18406350

3

Phospholipid transfer protein is regulated by liver X receptors in vivo.

Cao G, Beyer TP, Yang XP, Schmidt RJ, Zhang Y, Bensch WR, Kauffman RF, Gao H, Ryan TP, Liang Y, Eacho PI, Jiang XC. Cao G, et al. Among authors: bensch wr. J Biol Chem. 2002 Oct 18;277(42):39561-5. doi: 10.1074/jbc.M207187200. Epub 2002 Aug 9. J Biol Chem. 2002. PMID: 12177004 Free article.

4

Enlargement of high density lipoprotein in mice via liver X receptor activation requires apolipoprotein E and is abolished by cholesteryl ester transfer protein expression.

Jiang XC, Beyer TP, Li Z, Liu J, Quan W, Schmidt RJ, Zhang Y, Bensch WR, Eacho PI, Cao G. Jiang XC, et al. Among authors: bensch wr. J Biol Chem. 2003 Dec 5;278(49):49072-8. doi: 10.1074/jbc.M304274200. Epub 2003 Aug 28. J Biol Chem. 2003. PMID: 12947111 Free article.

5

Coadministration of a liver X receptor agonist and a peroxisome proliferator activator receptor-alpha agonist in Mice: effects of nuclear receptor interplay on high-density lipoprotein and triglyceride metabolism in vivo.

Beyer TP, Schmidt RJ, Foxworthy P, Zhang Y, Dai J, Bensch WR, Kauffman RF, Gao H, Ryan TP, Jiang XC, Karathanasis SK, Eacho PI, Cao G. Beyer TP, et al. Among authors: bensch wr. J Pharmacol Exp Ther. 2004 Jun;309(3):861-8. doi: 10.1124/jpet.103.064535. Epub 2004 Feb 11. J Pharmacol Exp Ther. 2004. PMID: 14960661

6

Identification and characterization of a major liver lysophosphatidylcholine acyltransferase.

Zhao Y, Chen YQ, Bonacci TM, Bredt DS, Li S, Bensch WR, Moller DE, Kowala M, Konrad RJ, Cao G. Zhao Y, et al. Among authors: bensch wr. J Biol Chem. 2008 Mar 28;283(13):8258-65. doi: 10.1074/jbc.M710422200. Epub 2008 Jan 14. J Biol Chem. 2008. PMID: 18195019 Free article.

7

Effects of LY295427, a low-density lipoprotein (LDL) receptor up-regulator, on LDL receptor gene transcription and cholesterol metabolism in normal and hypercholesterolemic hamsters.

Bensch WR, Gadski RA, Bean JS, Beavers LS, Schmidt RJ, Perry DN, Murphy AT, McClure DB, Eacho PI, Breau AP, Archer RA, Kauffman RF. Bensch WR, et al. J Pharmacol Exp Ther. 1999 Apr;289(1):85-92. J Pharmacol Exp Ther. 1999. PMID: 10086991

8

Synthesis and biological evaluation of a new series of sterols as potential hypocholesterolemic agents.

Lin HS, Rampersaud AA, Archer RA, Pawlak JM, Beavers LS, Schmidt RJ, Kauffman RF, Bensch WR, Bumol TF, Apelgren LD, et al. Lin HS, et al. Among authors: bensch wr. J Med Chem. 1995 Jan 20;38(2):277-88. doi: 10.1021/jm00002a010. J Med Chem. 1995. PMID: 7830271

9

Inhibition of cholesteryl ester transfer protein in normocholesterolemic and hypercholesterolemic hamsters: effects on HDL subspecies, quantity, and apolipoprotein distribution.

Evans GF, Bensch WR, Apelgren LD, Bailey D, Kauffman RF, Bumol TF, Zuckerman SH. Evans GF, et al. Among authors: bensch wr. J Lipid Res. 1994 Sep;35(9):1634-45. J Lipid Res. 1994. PMID: 7806977 Free article.

10

Identification of a novel selective peroxisome proliferator-activated receptor alpha agonist, 2-methyl-2-(4-{3-[1-(4-methylbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl]propyl}phenoxy)propanoic acid (LY518674), that produces marked changes in serum lipids and apolipoprotein A-1 expression.

Singh JP, Kauffman R, Bensch W, Wang G, McClelland P, Bean J, Montrose C, Mantlo N, Wagle A. Singh JP, et al. Mol Pharmacol. 2005 Sep;68(3):763-8. doi: 10.1124/mol.105.010991. Epub 2005 Jun 2. Mol Pharmacol. 2005. PMID: 15933217

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