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Evacetrapib is a novel, potent, and selective inhibitor of cholesteryl ester transfer protein that elevates HDL cholesterol without inducing aldosterone or increasing blood pressure.
Cao G, Beyer TP, Zhang Y, Schmidt RJ, Chen YQ, Cockerham SL, Zimmerman KM, Karathanasis SK, Cannady EA, Fields T, Mantlo NB. Cao G, et al. Among authors: schmidt rj. J Lipid Res. 2011 Dec;52(12):2169-2176. doi: 10.1194/jlr.M018069. Epub 2011 Sep 25. J Lipid Res. 2011. PMID: 21957197 Free PMC article.
Phospholipid transfer protein is regulated by liver X receptors in vivo.
Cao G, Beyer TP, Yang XP, Schmidt RJ, Zhang Y, Bensch WR, Kauffman RF, Gao H, Ryan TP, Liang Y, Eacho PI, Jiang XC. Cao G, et al. Among authors: schmidt rj. J Biol Chem. 2002 Oct 18;277(42):39561-5. doi: 10.1074/jbc.M207187200. Epub 2002 Aug 9. J Biol Chem. 2002. PMID: 12177004 Free article.
Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.
Cao G, Liang Y, Broderick CL, Oldham BA, Beyer TP, Schmidt RJ, Zhang Y, Stayrook KR, Suen C, Otto KA, Miller AR, Dai J, Foxworthy P, Gao H, Ryan TP, Jiang XC, Burris TP, Eacho PI, Etgen GJ. Cao G, et al. Among authors: schmidt rj. J Biol Chem. 2003 Jan 10;278(2):1131-6. doi: 10.1074/jbc.M210208200. Epub 2002 Oct 31. J Biol Chem. 2003. PMID: 12414791 Free article.
525 results