Rokicki MJ - Search Results

1

The role of cellular senescence in Werner syndrome: toward therapeutic intervention in human premature aging.

Davis T, Wyllie FS, Rokicki MJ, Bagley MC, Kipling D. Davis T, et al. Among authors: rokicki mj. Ann N Y Acad Sci. 2007 Apr;1100:455-69. doi: 10.1196/annals.1395.051. Ann N Y Acad Sci. 2007. PMID: 17460211 Review.

2

Rapid synthesis of VX-745: p38 MAP kinase inhibition in Werner syndrome cells.

Bagley MC, Davis T, Dix MC, Rokicki MJ, Kipling D. Bagley MC, et al. Among authors: rokicki mj. Bioorg Med Chem Lett. 2007 Sep 15;17(18):5107-10. doi: 10.1016/j.bmcl.2007.07.016. Epub 2007 Jul 13. Bioorg Med Chem Lett. 2007. PMID: 17659871

3

Synthesis and in vivo activity of MK2 and MK2 substrate-selective p38alpha(MAPK) inhibitors in Werner syndrome cells.

Davis T, Bagley MC, Dix MC, Murziani PG, Rokicki MJ, Widdowson CS, Zayed JM, Bachler MA, Kipling D. Davis T, et al. Among authors: rokicki mj. Bioorg Med Chem Lett. 2007 Dec 15;17(24):6832-5. doi: 10.1016/j.bmcl.2007.10.036. Epub 2007 Oct 17. Bioorg Med Chem Lett. 2007. PMID: 17964780

4

Synthesis of the highly selective p38 MAPK inhibitor UR-13756 for possible therapeutic use in Werner syndrome.

Bagley MC, Davis T, Rokicki MJ, Widdowson CS, Kipling D. Bagley MC, et al. Among authors: rokicki mj. Future Med Chem. 2010 Feb;2(2):193-201. doi: 10.4155/fmc.09.163. Future Med Chem. 2010. PMID: 21426186

5

Investigating the role of c-Jun N-terminal kinases in the proliferation of Werner syndrome fibroblasts using diaminopyridine inhibitors.

Davis T, Dix MC, Rokicki MJ, Brook AJ, Widdowson CS, Kipling D, Bagley MC. Davis T, et al. Among authors: rokicki mj. Chem Cent J. 2011 Dec 8;5(1):83. doi: 10.1186/1752-153X-5-83. Chem Cent J. 2011. PMID: 22152108 Free PMC article.

6

Activation of p38 MAP kinase and stress signalling in fibroblasts from the progeroid Rothmund-Thomson syndrome.

Davis T, Tivey HS, Brook AJ, Grimstead JW, Rokicki MJ, Kipling D. Davis T, et al. Among authors: rokicki mj. Age (Dordr). 2013 Oct;35(5):1767-83. doi: 10.1007/s11357-012-9476-9. Epub 2012 Sep 22. Age (Dordr). 2013. PMID: 23001818 Free PMC article.

7

p38 (MAPK) stress signalling in replicative senescence in fibroblasts from progeroid and genomic instability syndromes.

Tivey HS, Brook AJ, Rokicki MJ, Kipling D, Davis T. Tivey HS, et al. Among authors: rokicki mj. Biogerontology. 2013 Feb;14(1):47-62. doi: 10.1007/s10522-012-9407-2. Epub 2012 Oct 31. Biogerontology. 2013. PMID: 23112078 Free PMC article.

8

Evaluating the Role of p38 MAPK in the Accelerated Cell Senescence of Werner Syndrome Fibroblasts.

Davis T, Brook AJ, Rokicki MJ, Bagley MC, Kipling D. Davis T, et al. Among authors: rokicki mj. Pharmaceuticals (Basel). 2016 Apr 28;9(2):23. doi: 10.3390/ph9020023. Pharmaceuticals (Basel). 2016. PMID: 27136566 Free PMC article.

9

The effect of small-molecule inhibition of MAPKAPK2 on cell ageing phenotypes of fibroblasts from human Werner syndrome.

Davis T, Rokicki MJ, Bagley MC, Kipling D. Davis T, et al. Among authors: rokicki mj. Chem Cent J. 2013 Jan 29;7(1):18. doi: 10.1186/1752-153X-7-18. Chem Cent J. 2013. PMID: 23360642 Free PMC article.

10

Microwave-assisted synthesis of 5-aminopyrazol-4-yl ketones and the p38(MAPK) inhibitor RO3201195 for study in Werner syndrome cells.

Bagley MC, Davis T, Dix MC, Murziani PG, Rokicki MJ, Kipling D. Bagley MC, et al. Among authors: rokicki mj. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3745-8. doi: 10.1016/j.bmcl.2008.05.037. Epub 2008 May 16. Bioorg Med Chem Lett. 2008. PMID: 18539026

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