Mekel M - Search Results

1

Isolation and expression of a Malassezia globosa lipase gene, LIP1.

DeAngelis YM, Saunders CW, Johnstone KR, Reeder NL, Coleman CG, Kaczvinsky JR Jr, Gale C, Walter R, Mekel M, Lacey MP, Keough TW, Fieno A, Grant RA, Begley B, Sun Y, Fuentes G, Youngquist RS, Xu J, Dawson TL Jr. DeAngelis YM, et al. Among authors: mekel m. J Invest Dermatol. 2007 Sep;127(9):2138-46. doi: 10.1038/sj.jid.5700844. Epub 2007 Apr 26. J Invest Dermatol. 2007. PMID: 17460728 Free article.

2

Design and synthesis of a series of novel pyrazolopyridines as HIF-1alpha prolyl hydroxylase inhibitors.

Warshakoon NC, Wu S, Boyer A, Kawamoto R, Renock S, Xu K, Pokross M, Evdokimov AG, Zhou S, Winter C, Walter R, Mekel M. Warshakoon NC, et al. Among authors: mekel m. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5687-90. doi: 10.1016/j.bmcl.2006.08.017. Bioorg Med Chem Lett. 2006. PMID: 16908145

3

A novel series of imidazo[1,2-a]pyridine derivatives as HIF-1alpha prolyl hydroxylase inhibitors.

Warshakoon NC, Wu S, Boyer A, Kawamoto R, Sheville J, Renock S, Xu K, Pokross M, Evdokimov AG, Walter R, Mekel M. Warshakoon NC, et al. Among authors: mekel m. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5598-601. doi: 10.1016/j.bmcl.2006.08.089. Epub 2006 Sep 8. Bioorg Med Chem Lett. 2006. PMID: 16962772

4

Design and synthesis of substituted pyridine derivatives as HIF-1alpha prolyl hydroxylase inhibitors.

Warshakoon NC, Wu S, Boyer A, Kawamoto R, Sheville J, Bhatt RT, Renock S, Xu K, Pokross M, Zhou S, Walter R, Mekel M, Evdokimov AG, East S. Warshakoon NC, et al. Among authors: mekel m. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5616-20. doi: 10.1016/j.bmcl.2006.08.026. Bioorg Med Chem Lett. 2006. PMID: 16908149

5

Structure-based design, synthesis, and SAR evaluation of a new series of 8-hydroxyquinolines as HIF-1alpha prolyl hydroxylase inhibitors.

Warshakoon NC, Wu S, Boyer A, Kawamoto R, Sheville J, Renock S, Xu K, Pokross M, Zhou S, Winter C, Walter R, Mekel M, Evdokimov AG. Warshakoon NC, et al. Among authors: mekel m. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5517-22. doi: 10.1016/j.bmcl.2006.08.040. Epub 2006 Aug 22. Bioorg Med Chem Lett. 2006. PMID: 16931007

6

Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.

Evdokimov AG, Pokross M, Walter RL, Mekel M, Barnett BL, Amburgey J, Seibel WL, Soper SJ, Djung JF, Fairweather N, Diven C, Rastogi V, Grinius L, Klanke C, Siehnel R, Twinem T, Andrews R, Curnow A. Evdokimov AG, et al. Among authors: mekel m. Proteins. 2007 Feb 15;66(3):538-46. doi: 10.1002/prot.21207. Proteins. 2007. PMID: 17120228

7

The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-alpha) production.

Laughlin SK, Clark MP, Djung JF, Golebiowski A, Brugel TA, Sabat M, Bookland RG, Laufersweiler MJ, VanRens JC, Townes JA, De B, Hsieh LC, Xu SC, Walter RL, Mekel MJ, Janusz MJ. Laughlin SK, et al. Among authors: mekel mj. Bioorg Med Chem Lett. 2005 May 2;15(9):2399-403. doi: 10.1016/j.bmcl.2005.02.066. Bioorg Med Chem Lett. 2005. PMID: 15837333

8

The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck).

Sabat M, VanRens JC, Laufersweiler MJ, Brugel TA, Maier J, Golebiowski A, De B, Easwaran V, Hsieh LC, Walter RL, Mekel MJ, Evdokimov A, Janusz MJ. Sabat M, et al. Among authors: mekel mj. Bioorg Med Chem Lett. 2006 Dec 1;16(23):5973-7. doi: 10.1016/j.bmcl.2006.08.132. Epub 2006 Sep 25. Bioorg Med Chem Lett. 2006. PMID: 16997556

9

The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production.

Sabat M, Vanrens JC, Clark MP, Brugel TA, Maier J, Bookland RG, Laufersweiler MJ, Laughlin SK, Golebiowski A, De B, Hsieh LC, Walter RL, Mekel MJ, Janusz MJ. Sabat M, et al. Among authors: mekel mj. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4360-5. doi: 10.1016/j.bmcl.2006.05.050. Epub 2006 Jun 5. Bioorg Med Chem Lett. 2006. PMID: 16750367

10

Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-gamma binding agents with potential application to the treatment of osteoporosis.

Hopkins CR, O'neil SV, Laufersweiler MC, Wang Y, Pokross M, Mekel M, Evdokimov A, Walter R, Kontoyianni M, Petrey ME, Sabatakos G, Roesgen JT, Richardson E, Demuth TP Jr. Hopkins CR, et al. Among authors: mekel m. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5659-63. doi: 10.1016/j.bmcl.2006.08.003. Epub 2006 Aug 21. Bioorg Med Chem Lett. 2006. PMID: 16919947

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