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Page 1
Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 5' elements.
Young HW, Williams OW, Chandra D, Bellinghausen LK, Pérez G, Suárez A, Tuvim MJ, Roy MG, Alexander SN, Moghaddam SJ, Adachi R, Blackburn MR, Dickey BF, Evans CM. Young HW, et al. Among authors: williams ow. Am J Respir Cell Mol Biol. 2007 Sep;37(3):273-90. doi: 10.1165/rcmb.2005-0460OC. Epub 2007 Apr 26. Am J Respir Cell Mol Biol. 2007. PMID: 17463395 Free PMC article.
Mucin is produced by clara cells in the proximal airways of antigen-challenged mice.
Evans CM, Williams OW, Tuvim MJ, Nigam R, Mixides GP, Blackburn MR, DeMayo FJ, Burns AR, Smith C, Reynolds SD, Stripp BR, Dickey BF. Evans CM, et al. Among authors: williams ow. Am J Respir Cell Mol Biol. 2004 Oct;31(4):382-94. doi: 10.1165/rcmb.2004-0060OC. Epub 2004 Jun 10. Am J Respir Cell Mol Biol. 2004. PMID: 15191915 Free PMC article.
Airway mucus: From production to secretion.
Williams OW, Sharafkhaneh A, Kim V, Dickey BF, Evans CM. Williams OW, et al. Am J Respir Cell Mol Biol. 2006 May;34(5):527-36. doi: 10.1165/rcmb.2005-0436SF. Epub 2006 Jan 13. Am J Respir Cell Mol Biol. 2006. PMID: 16415249 Free PMC article. Review.
The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.
Evans CM, Raclawska DS, Ttofali F, Liptzin DR, Fletcher AA, Harper DN, McGing MA, McElwee MM, Williams OW, Sanchez E, Roy MG, Kindrachuk KN, Wynn TA, Eltzschig HK, Blackburn MR, Tuvim MJ, Janssen WJ, Schwartz DA, Dickey BF. Evans CM, et al. Among authors: williams ow. Nat Commun. 2015 Feb 17;6:6281. doi: 10.1038/ncomms7281. Nat Commun. 2015. PMID: 25687754 Free PMC article.