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CRTC3 links catecholamine signalling to energy balance.
Song Y, Altarejos J, Goodarzi MO, Inoue H, Guo X, Berdeaux R, Kim JH, Goode J, Igata M, Paz JC, Hogan MF, Singh PK, Goebel N, Vera L, Miller N, Cui J, Jones MR; CHARGE Consortium; GIANT Consortium; Chen YD, Taylor KD, Hsueh WA, Rotter JI, Montminy M. Song Y, et al. Among authors: berdeaux r. Nature. 2010 Dec 16;468(7326):933-9. doi: 10.1038/nature09564. Nature. 2010. PMID: 21164481 Free PMC article.
The AMPK-Related Kinases SIK1 and SIK3 Mediate Key Tumor-Suppressive Effects of LKB1 in NSCLC.
Hollstein PE, Eichner LJ, Brun SN, Kamireddy A, Svensson RU, Vera LI, Ross DS, Rymoff TJ, Hutchins A, Galvez HM, Williams AE, Shokhirev MN, Screaton RA, Berdeaux R, Shaw RJ. Hollstein PE, et al. Among authors: berdeaux r. Cancer Discov. 2019 Nov;9(11):1606-1627. doi: 10.1158/2159-8290.CD-18-1261. Epub 2019 Jul 26. Cancer Discov. 2019. PMID: 31350328 Free PMC article.
Regulation of SIK1 abundance and stability is critical for myogenesis.
Stewart R, Akhmedov D, Robb C, Leiter C, Berdeaux R. Stewart R, et al. Among authors: berdeaux r. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):117-22. doi: 10.1073/pnas.1212676110. Epub 2012 Dec 19. Proc Natl Acad Sci U S A. 2013. PMID: 23256157 Free PMC article.
The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure.
Wu VH, Yung BS, Faraji F, Saddawi-Konefka R, Wang Z, Wenzel AT, Song MJ, Pagadala MS, Clubb LM, Chiou J, Sinha S, Matic M, Raimondi F, Hoang TS, Berdeaux R, Vignali DAA, Iglesias-Bartolome R, Carter H, Ruppin E, Mesirov JP, Gutkind JS. Wu VH, et al. Among authors: berdeaux r. Nat Immunol. 2023 Aug;24(8):1318-1330. doi: 10.1038/s41590-023-01529-7. Epub 2023 Jun 12. Nat Immunol. 2023. PMID: 37308665 Free PMC article.
Skeletal muscle salt inducible kinase 1 promotes insulin resistance in obesity.
Nixon M, Stewart-Fitzgibbon R, Fu J, Akhmedov D, Rajendran K, Mendoza-Rodriguez MG, Rivera-Molina YA, Gibson M, Berglund ED, Justice NJ, Berdeaux R. Nixon M, et al. Among authors: berdeaux r. Mol Metab. 2015 Nov 6;5(1):34-46. doi: 10.1016/j.molmet.2015.10.004. eCollection 2016 Jan. Mol Metab. 2015. PMID: 26844205 Free PMC article.
MEF2 is an in vivo immune-metabolic switch.
Clark RI, Tan SW, Péan CB, Roostalu U, Vivancos V, Bronda K, Pilátová M, Fu J, Walker DW, Berdeaux R, Geissmann F, Dionne MS. Clark RI, et al. Among authors: berdeaux r. Cell. 2013 Oct 10;155(2):435-47. doi: 10.1016/j.cell.2013.09.007. Epub 2013 Sep 26. Cell. 2013. PMID: 24075010 Free PMC article.
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