Lubin ML - Search Results

1

Attenuated cold sensitivity in TRPM8 null mice.

Colburn RW, Lubin ML, Stone DJ Jr, Wang Y, Lawrence D, D'Andrea MR, Brandt MR, Liu Y, Flores CM, Qin N. Colburn RW, et al. Among authors: lubin ml. Neuron. 2007 May 3;54(3):379-86. doi: 10.1016/j.neuron.2007.04.017. Neuron. 2007. PMID: 17481392 Free article.

2

Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine.

Liu Y, Lubin ML, Reitz TL, Wang Y, Colburn RW, Flores CM, Qin N. Liu Y, et al. Among authors: lubin ml. Eur J Pharmacol. 2006 Jan 13;530(1-2):23-32. doi: 10.1016/j.ejphar.2005.11.033. Epub 2005 Dec 28. Eur J Pharmacol. 2006. PMID: 16386244

3

Design and optimization of benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonists.

Parks DJ, Parsons WH, Colburn RW, Meegalla SK, Ballentine SK, Illig CR, Qin N, Liu Y, Hutchinson TL, Lubin ML, Stone DJ Jr, Baker JF, Schneider CR, Ma J, Damiano BP, Flores CM, Player MR. Parks DJ, et al. Among authors: lubin ml. J Med Chem. 2011 Jan 13;54(1):233-47. doi: 10.1021/jm101075v. Epub 2010 Dec 3. J Med Chem. 2011. PMID: 21128593

4

Discovery of vinylcycloalkyl-substituted benzimidazole TRPM8 antagonists effective in the treatment of cold allodynia.

Calvo RR, Meegalla SK, Parks DJ, Parsons WH, Ballentine SK, Lubin ML, Schneider C, Colburn RW, Flores CM, Player MR. Calvo RR, et al. Among authors: lubin ml. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1903-7. doi: 10.1016/j.bmcl.2012.01.060. Epub 2012 Jan 28. Bioorg Med Chem Lett. 2012. PMID: 22330635

5

Arylglycine derivatives as potent transient receptor potential melastatin 8 (TRPM8) antagonists.

Zhu B, Xia M, Xu X, Ludovici DW, Tennakoon M, Youngman MA, Matthews JM, Dax SL, Colburn RW, Qin N, Hutchinson TL, Lubin ML, Brandt MR, Stone DJ, Flores CM, Macielag MJ. Zhu B, et al. Among authors: lubin ml. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2234-7. doi: 10.1016/j.bmcl.2013.01.062. Epub 2013 Feb 4. Bioorg Med Chem Lett. 2013. PMID: 23411075

6

TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons.

Qin N, Neeper MP, Liu Y, Hutchinson TL, Lubin ML, Flores CM. Qin N, et al. Among authors: lubin ml. J Neurosci. 2008 Jun 11;28(24):6231-8. doi: 10.1523/JNEUROSCI.0504-08.2008. J Neurosci. 2008. PMID: 18550765 Free PMC article.

7

An integrated multiassay approach to the discovery of small-molecule N-type voltage-gated calcium channel antagonists.

Finley MF, Lubin ML, Neeper MP, Beck E, Liu Y, Flores CM, Qin N. Finley MF, et al. Among authors: lubin ml. Assay Drug Dev Technol. 2010 Dec;8(6):685-94. doi: 10.1089/adt.2010.0311. Epub 2010 Nov 4. Assay Drug Dev Technol. 2010. PMID: 21050074

8

The design and synthesis of novel, phosphonate-containing transient receptor potential melastatin 8 (TRPM8) antagonists.

Matthews JM, Qin N, Colburn RW, Dax SL, Hawkins M, McNally JJ, Reany L, Youngman MA, Baker J, Hutchinson T, Liu Y, Lubin ML, Neeper M, Brandt MR, Stone DJ, Flores CM. Matthews JM, et al. Among authors: lubin ml. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2922-6. doi: 10.1016/j.bmcl.2012.02.060. Epub 2012 Feb 27. Bioorg Med Chem Lett. 2012. PMID: 22421018

9

Discovery and SAR of novel tetrahydropyrrolo[3,4-c]pyrazoles as inhibitors of the N-type calcium channel.

Winters MP, Subasinghe N, Wall M, Beck E, Brandt MR, Finley MF, Liu Y, Lubin ML, Neeper MP, Qin N, Flores CM, Sui Z. Winters MP, et al. Among authors: lubin ml. Bioorg Med Chem Lett. 2014 May 1;24(9):2053-6. doi: 10.1016/j.bmcl.2014.03.062. Epub 2014 Mar 27. Bioorg Med Chem Lett. 2014. PMID: 24726802

10

Discovery and SAR of a novel series of 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles as N-type calcium channel inhibitors.

Winters MP, Subasinghe N, Wall M, Beck E, Brandt MR, Finley MF, Liu Y, Lubin ML, Neeper MP, Qin N, Flores CM, Sui Z. Winters MP, et al. Among authors: lubin ml. Bioorg Med Chem Lett. 2014 May 1;24(9):2057-61. doi: 10.1016/j.bmcl.2014.03.063. Epub 2014 Mar 28. Bioorg Med Chem Lett. 2014. PMID: 24726803

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