Sorg UR - Search Results

1

O6-methylguanine-DNA-methyltransferase (MGMT) gene therapy targeting haematopoietic stem cells: studies addressing safety issues.

Sorg UR, Kleff V, Fanaei S, Schumann A, Moellmann M, Opalka B, Thomale J, Moritz T. Sorg UR, et al. DNA Repair (Amst). 2007 Aug 1;6(8):1197-209. doi: 10.1016/j.dnarep.2007.03.021. Epub 2007 May 11. DNA Repair (Amst). 2007. PMID: 17499560

2

Reliable generation of stable high titer producer cell lines for gene therapy.

Rattmann I, Kleff V, Feldmann A, Ludwig C, Sorg UR, Opalka B, Moritz T, Flasshove M. Rattmann I, et al. Among authors: sorg ur. Intervirology. 2007;50(3):197-203. doi: 10.1159/000099218. Epub 2007 Feb 2. Intervirology. 2007. PMID: 17283445

3

Hematoprotection and enrichment of transduced cells in vivo after gene transfer of MGMT(P140K) into hematopoietic stem cells.

Jansen M, Sorg UR, Ragg S, Flasshove M, Seeber S, Williams DA, Moritz T. Jansen M, et al. Among authors: sorg ur. Cancer Gene Ther. 2002 Sep;9(9):737-46. doi: 10.1038/sj.cgt.7700490. Cancer Gene Ther. 2002. PMID: 12189523

4

Stringent regulation of DNA repair during human hematopoietic differentiation: a gene expression and functional analysis.

Bracker TU, Giebel B, Spanholtz J, Sorg UR, Klein-Hitpass L, Moritz T, Thomale J. Bracker TU, et al. Among authors: sorg ur. Stem Cells. 2006 Mar;24(3):722-30. doi: 10.1634/stemcells.2005-0227. Epub 2005 Sep 29. Stem Cells. 2006. PMID: 16195417

5

Gene transfer of cytidine deaminase protects myelopoiesis from cytidine analogs in an in vivo murine transplant model.

Rattmann I, Kleff V, Sorg UR, Bardenheuer W, Brueckner A, Hilger RA, Opalka B, Seeber S, Flasshove M, Moritz T. Rattmann I, et al. Among authors: sorg ur. Blood. 2006 Nov 1;108(9):2965-71. doi: 10.1182/blood-2006-03-011734. Epub 2006 Jul 11. Blood. 2006. PMID: 16835384 Free article.

6

Gene therapy of beta(c)-deficient pulmonary alveolar proteinosis (beta(c)-PAP): studies in a murine in vivo model.

Kleff V, Sorg UR, Bury C, Suzuki T, Rattmann I, Jerabek-Willemsen M, Poremba C, Flasshove M, Opalka B, Trapnell B, Dirksen U, Moritz T. Kleff V, et al. Among authors: sorg ur. Mol Ther. 2008 Apr;16(4):757-64. doi: 10.1038/mt.2008.7. Epub 2008 Mar 4. Mol Ther. 2008. PMID: 18334984 Free article.

7

Clonal inventory screens uncover monoclonality following serial transplantation of MGMT P140K-transduced stem cells and dose-intense chemotherapy.

Giordano FA, Sorg UR, Appelt JU, Lachmann N, Bleier S, Roeder I, Kleff V, Flasshove M, Zeller WJ, Allgayer H, von Kalle C, Fruehauf S, Moritz T, Laufs S. Giordano FA, et al. Among authors: sorg ur. Hum Gene Ther. 2011 Jun;22(6):697-710. doi: 10.1089/hum.2010.088. Epub 2011 Apr 11. Hum Gene Ther. 2011. PMID: 21319998

8

Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones.

Jansen M, Bardenheuer W, Sorg UR, Seeber S, Flasshove M, Moritz T. Jansen M, et al. Among authors: sorg ur. Eur J Haematol. 2001 Jul;67(1):2-13. doi: 10.1034/j.1600-0609.2001.067001002.x. Eur J Haematol. 2001. PMID: 11553261

9

Efficient protection from methotrexate toxicity and selection of transduced human hematopoietic cells following gene transfer of dihydrofolate reductase mutants.

Meisel R, Bardenheuer W, Strehblow C, Sorg UR, Elmaagacli A, Seeber S, Flasshove M, Moritz T. Meisel R, et al. Among authors: sorg ur. Exp Hematol. 2003 Dec;31(12):1215-22. doi: 10.1016/j.exphem.2003.09.012. Exp Hematol. 2003. PMID: 14662327 Free article.

10

Gene Therapy of βc-Deficient Pulmonary Alveolar Proteinosis (βc-PAP): Studies in a Murine in vivo Model.

Kleff V, Sorg UR, Bury C, Suzuki T, Rattmann I, Jerabek-Willemsen M, Poremba C, Flasshove M, Opalka B, Trapnell B, Dirksen U, Moritz T. Kleff V, et al. Among authors: sorg ur. Mol Ther. 2008 Apr;16(4):757-764. doi: 10.1038/mt.2008.7. Epub 2016 Dec 8. Mol Ther. 2008. PMID: 28178466

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