Dean BJ - Search Results

1

The pharmacokinetics and disposition of MK-0524, a Prosglandin D2 Receptor 1 antagonist, in rats, dogs and monkeys.

Chang SW, Reddy V, Pereira T, Dean BJ, Xia YQ, Seto C, Franklin RB, Karanam BV. Chang SW, et al. Among authors: dean bj. Xenobiotica. 2007 May;37(5):514-33. doi: 10.1080/00498250601175565. Xenobiotica. 2007. PMID: 17523054

2

Substance P receptor antagonist I: conversion of phosphoramidate prodrug after i.v. administration to rats and dogs.

Huskey SE, Luffer-Atlas D, Dean BJ, McGowan EM, Feeney WP, Chiu SH. Huskey SE, et al. Among authors: dean bj. Drug Metab Dispos. 1999 Nov;27(11):1367-73. Drug Metab Dispos. 1999. PMID: 10534323

3

Isolation and characterization of a UDP-glucuronosyltransferase (UGT1A01) cloned from female rhesus monkey.

Dean B, Chang S, Stevens J, Thomas PE, King C. Dean B, et al. Arch Biochem Biophys. 2002 Jun 15;402(2):289-95. doi: 10.1016/S0003-9861(02)00084-X. Arch Biochem Biophys. 2002. PMID: 12051676

4

Brain penetration of aprepitant, a substance P receptor antagonist, in ferrets.

Huskey SE, Dean BJ, Bakhtiar R, Sanchez RI, Tattersall FD, Rycroft W, Hargreaves R, Watt AP, Chicchi GG, Keohane C, Hora DF, Chiu SH. Huskey SE, et al. Among authors: dean bj. Drug Metab Dispos. 2003 Jun;31(6):785-91. doi: 10.1124/dmd.31.6.785. Drug Metab Dispos. 2003. PMID: 12756213

5

The metabolic disposition of aprepitant, a substance P receptor antagonist, in rats and dogs.

Huskey SE, Dean BJ, Doss GA, Wang Z, Hop CE, Anari R, Finke PE, Robichaud AJ, Zhang M, Wang B, Strauss JR, Cunningham PK, Feeney WP, Franklin RB, Baillie TA, Chiu SH. Huskey SE, et al. Among authors: dean bj. Drug Metab Dispos. 2004 Feb;32(2):246-58. doi: 10.1124/dmd.32.2.246. Drug Metab Dispos. 2004. PMID: 14744948

6

Identification of UGT2B9*2 and UGT2B33 isolated from female rhesus monkey liver.

Dean B, Arison B, Chang S, Thomas PE, King C. Dean B, et al. Arch Biochem Biophys. 2004 Jun 1;426(1):55-62. doi: 10.1016/j.abb.2004.03.035. Arch Biochem Biophys. 2004. PMID: 15130782

7

Glucuronidation, oxidative metabolism, and bioactivation of enterolactone in rhesus monkeys.

Dean B, Chang S, Doss GA, King C, Thomas PE. Dean B, et al. Arch Biochem Biophys. 2004 Sep 15;429(2):244-51. doi: 10.1016/j.abb.2004.06.023. Arch Biochem Biophys. 2004. PMID: 15313229

8

Metabolism of MK-0524, a prostaglandin D2 receptor 1 antagonist, in microsomes and hepatocytes from preclinical species and humans.

Dean BJ, Chang S, Silva Elipe MV, Xia YQ, Braun M, Soli E, Zhao Y, Franklin RB, Karanam B. Dean BJ, et al. Drug Metab Dispos. 2007 Feb;35(2):283-92. doi: 10.1124/dmd.106.011551. Epub 2006 Nov 28. Drug Metab Dispos. 2007. PMID: 17132765

9

Absorption, metabolism, and excretion of [(14)C]MK-0524, a prostaglandin D(2) receptor antagonist, in humans.

Karanam B, Madeira M, Bradley S, Wenning L, Desai R, Soli E, Schenk D, Jones A, Dean B, Doss G, Garrett G, Crumley T, Nirula A, Lai E. Karanam B, et al. Drug Metab Dispos. 2007 Jul;35(7):1196-202. doi: 10.1124/dmd.107.014696. Epub 2007 Apr 12. Drug Metab Dispos. 2007. PMID: 17431030 Clinical Trial.

10

Benzazepinone Nav1.7 blockers: potential treatments for neuropathic pain.

Hoyt SB, London C, Ok H, Gonzalez E, Duffy JL, Abbadie C, Dean B, Felix JP, Garcia ML, Jochnowitz N, Karanam BV, Li X, Lyons KA, McGowan E, Macintyre DE, Martin WJ, Priest BT, Smith MM, Tschirret-Guth R, Warren VA, Williams BS, Kaczorowski GJ, Parsons WH. Hoyt SB, et al. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6172-7. doi: 10.1016/j.bmcl.2007.09.032. Epub 2007 Sep 11. Bioorg Med Chem Lett. 2007. PMID: 17889534

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