Mihara M - Search Results

1

Interleukin-6 receptor-mediated activation of signal transducer and activator of transcription-3 (STAT3) promotes choroidal neovascularization.

Izumi-Nagai K, Nagai N, Ozawa Y, Mihara M, Ohsugi Y, Kurihara T, Koto T, Satofuka S, Inoue M, Tsubota K, Okano H, Oike Y, Ishida S. Izumi-Nagai K, et al. Among authors: mihara m. Am J Pathol. 2007 Jun;170(6):2149-58. doi: 10.2353/ajpath.2007.061018. Am J Pathol. 2007. PMID: 17525280 Free PMC article.

2

Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons.

Yamashita T, Sawamoto K, Suzuki S, Suzuki N, Adachi K, Kawase T, Mihara M, Ohsugi Y, Abe K, Okano H. Yamashita T, et al. Among authors: mihara m. J Neurochem. 2005 Jul;94(2):459-68. doi: 10.1111/j.1471-4159.2005.03227.x. J Neurochem. 2005. PMID: 15998296 Free article.

3

Blockade of interleukin-6 signaling suppressed cochlear inflammatory response and improved hearing impairment in noise-damaged mice cochlea.

Wakabayashi K, Fujioka M, Kanzaki S, Okano HJ, Shibata S, Yamashita D, Masuda M, Mihara M, Ohsugi Y, Ogawa K, Okano H. Wakabayashi K, et al. Among authors: mihara m. Neurosci Res. 2010 Apr;66(4):345-52. doi: 10.1016/j.neures.2009.12.008. Epub 2009 Dec 21. Neurosci Res. 2010. PMID: 20026135

4

Blockade of interleukin-6 receptor suppresses reactive astrogliosis and ameliorates functional recovery in experimental spinal cord injury.

Okada S, Nakamura M, Mikami Y, Shimazaki T, Mihara M, Ohsugi Y, Iwamoto Y, Yoshizaki K, Kishimoto T, Toyama Y, Okano H. Okada S, et al. Among authors: mihara m. J Neurosci Res. 2004 Apr 15;76(2):265-76. doi: 10.1002/jnr.20044. J Neurosci Res. 2004. PMID: 15048924

5

The therapy of autoimmune diseases by anti-interleukin-6 receptor antibody.

Mihara M, Nishimoto N, Ohsugi Y. Mihara M, et al. Expert Opin Biol Ther. 2005 May;5(5):683-90. doi: 10.1517/14712598.5.5.683. Expert Opin Biol Ther. 2005. PMID: 15934843 Review.

6

Tocilizumab, a humanized anti-interleukin-6 receptor antibody, for treatment of rheumatoid arthritis.

Mihara M, Ohsugi Y, Kishimoto T. Mihara M, et al. Open Access Rheumatol. 2011 Feb 25;3:19-29. doi: 10.2147/OARRR.S17118. eCollection 2011. Open Access Rheumatol. 2011. PMID: 27790001 Free PMC article. Review.

7

Evidence for the role of Th17 cell inhibition in the prevention of autoimmune diseases by anti-interluekin-6 receptor antibody.

Mihara M, Ohsugi Y, Kishimoto T. Mihara M, et al. Biofactors. 2009 Jan-Feb;35(1):47-51. doi: 10.1002/biof.9. Biofactors. 2009. PMID: 19319845 Review.

8

Possible role of IL-6 in pathogenesis of immune complex-mediated glomerulonephritis in NZB/W F1 mice: induction of IgG class anti-DNA autoantibody production.

Mihara M, Ohsugi Y. Mihara M, et al. Int Arch Allergy Appl Immunol. 1990;93(1):89-92. doi: 10.1159/000235285. Int Arch Allergy Appl Immunol. 1990. PMID: 2086490

9

IL-6-soluble IL-6 receptor complex inhibits the proliferation of dermal fibroblasts.

Mihara M, Moriya Y, Ohsugi Y. Mihara M, et al. Int J Immunopharmacol. 1996 Jan;18(1):89-94. doi: 10.1016/0192-0561(95)00106-9. Int J Immunopharmacol. 1996. PMID: 8732437

10

An immunomodulating anti-rheumatic drug, lobenzarit disodium (CCA): inhibition of polyclonal B-cell activation and prevention of autoimmune disease in MRL/Mp-lpr/lpr mice.

Mihara M, Nakano T, Ohsugi Y. Mihara M, et al. Clin Immunol Immunopathol. 1987 Dec;45(3):366-74. doi: 10.1016/0090-1229(87)90089-4. Clin Immunol Immunopathol. 1987. PMID: 3500002

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