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Activation of inwardly rectifying Kir2.x potassium channels by beta 3-adrenoceptors is mediated via different signaling pathways with a predominant role of PKC for Kir2.1 and of PKA for Kir2.2.
Scherer D, Kiesecker C, Kulzer M, Günth M, Scholz EP, Kathöfer S, Thomas D, Maurer M, Kreuzer J, Bauer A, Katus HA, Karle CA, Zitron E. Scherer D, et al. Among authors: bauer a. Naunyn Schmiedebergs Arch Pharmacol. 2007 Jul;375(5):311-22. doi: 10.1007/s00210-007-0167-5. Epub 2007 May 30. Naunyn Schmiedebergs Arch Pharmacol. 2007. PMID: 17534603
Anticholinergic antiparkinson drug orphenadrine inhibits HERG channels: block attenuation by mutations of the pore residues Y652 or F656.
Scholz EP, Konrad FM, Weiss DL, Zitron E, Kiesecker C, Bloehs R, Kulzer M, Thomas D, Kathöfer S, Bauer A, Maurer MH, Seemann G, Katus HA, Karle CA. Scholz EP, et al. Among authors: bauer a. Naunyn Schmiedebergs Arch Pharmacol. 2007 Dec;376(4):275-84. doi: 10.1007/s00210-007-0202-6. Epub 2007 Oct 27. Naunyn Schmiedebergs Arch Pharmacol. 2007. PMID: 17965852
Inhibition of cardiac hERG potassium channels by tetracyclic antidepressant mianserin.
Scherer D, von Löwenstern K, Zitron E, Scholz EP, Bloehs R, Kathöfer S, Thomas D, Bauer A, Katus HA, Karle CA, Kiesecker C. Scherer D, et al. Among authors: bauer a. Naunyn Schmiedebergs Arch Pharmacol. 2008 Jul;378(1):73-83. doi: 10.1007/s00210-008-0289-4. Epub 2008 May 6. Naunyn Schmiedebergs Arch Pharmacol. 2008. PMID: 18458880
3,090 results