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Activation of inwardly rectifying Kir2.x potassium channels by beta 3-adrenoceptors is mediated via different signaling pathways with a predominant role of PKC for Kir2.1 and of PKA for Kir2.2.
Scherer D, Kiesecker C, Kulzer M, Günth M, Scholz EP, Kathöfer S, Thomas D, Maurer M, Kreuzer J, Bauer A, Katus HA, Karle CA, Zitron E. Scherer D, et al. Among authors: gunth m. Naunyn Schmiedebergs Arch Pharmacol. 2007 Jul;375(5):311-22. doi: 10.1007/s00210-007-0167-5. Epub 2007 May 30. Naunyn Schmiedebergs Arch Pharmacol. 2007. PMID: 17534603