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Activation of inwardly rectifying Kir2.x potassium channels by beta 3-adrenoceptors is mediated via different signaling pathways with a predominant role of PKC for Kir2.1 and of PKA for Kir2.2.
Scherer D, Kiesecker C, Kulzer M, Günth M, Scholz EP, Kathöfer S, Thomas D, Maurer M, Kreuzer J, Bauer A, Katus HA, Karle CA, Zitron E. Scherer D, et al. Among authors: kiesecker c. Naunyn Schmiedebergs Arch Pharmacol. 2007 Jul;375(5):311-22. doi: 10.1007/s00210-007-0167-5. Epub 2007 May 30. Naunyn Schmiedebergs Arch Pharmacol. 2007. PMID: 17534603
Drug binding to aromatic residues in the HERG channel pore cavity as possible explanation for acquired Long QT syndrome by antiparkinsonian drug budipine.
Scholz EP, Zitron E, Kiesecker C, Lueck S, Kathöfer S, Thomas D, Weretka S, Peth S, Kreye VA, Schoels W, Katus HA, Kiehn J, Karle CA. Scholz EP, et al. Among authors: kiesecker c. Naunyn Schmiedebergs Arch Pharmacol. 2003 Nov;368(5):404-14. doi: 10.1007/s00210-003-0805-5. Epub 2003 Oct 14. Naunyn Schmiedebergs Arch Pharmacol. 2003. PMID: 14557918
Inhibition of cardiac HERG potassium channels by the atypical antidepressant trazodone.
Zitron E, Kiesecker C, Scholz E, Lück S, Bloehs R, Kathöfer S, Thomas D, Kiehn J, Kreye VA, Katus HA, Schoels W, Karle CA. Zitron E, et al. Among authors: kiesecker c. Naunyn Schmiedebergs Arch Pharmacol. 2004 Aug;370(2):146-56. doi: 10.1007/s00210-004-0952-3. Epub 2004 Jul 29. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 15322737
Class Ia anti-arrhythmic drug ajmaline blocks HERG potassium channels: mode of action.
Kiesecker C, Zitron E, Lück S, Bloehs R, Scholz EP, Kathöfer S, Thomas D, Kreye VA, Katus HA, Schoels W, Karle CA, Kiehn J. Kiesecker C, et al. Naunyn Schmiedebergs Arch Pharmacol. 2004 Dec;370(6):423-35. doi: 10.1007/s00210-004-0976-8. Epub 2004 Oct 30. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 15599706
Inhibition of cardiac HERG channels by grapefruit flavonoid naringenin: implications for the influence of dietary compounds on cardiac repolarisation.
Scholz EP, Zitron E, Kiesecker C, Lück S, Thomas D, Kathöfer S, Kreye VA, Katus HA, Kiehn J, Schoels W, Karle CA. Scholz EP, et al. Among authors: kiesecker c. Naunyn Schmiedebergs Arch Pharmacol. 2005 Jun;371(6):516-25. doi: 10.1007/s00210-005-1069-z. Epub 2005 Jul 9. Naunyn Schmiedebergs Arch Pharmacol. 2005. PMID: 16007460
21 results