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Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses.
Beyer RP, Fry RC, Lasarev MR, McConnachie LA, Meira LB, Palmer VS, Powell CL, Ross PK, Bammler TK, Bradford BU, Cranson AB, Cunningham ML, Fannin RD, Higgins GM, Hurban P, Kayton RJ, Kerr KF, Kosyk O, Lobenhofer EK, Sieber SO, Vliet PA, Weis BK, Wolfinger R, Woods CG, Freedman JH, Linney E, Kaufmann WK, Kavanagh TJ, Paules RS, Rusyn I, Samson LD, Spencer PS, Suk W, Tennant RJ, Zarbl H; Members of the Toxicogenomics Research Consortium. Beyer RP, et al. Among authors: kosyk o. Toxicol Sci. 2007 Sep;99(1):326-37. doi: 10.1093/toxsci/kfm150. Epub 2007 Jun 11. Toxicol Sci. 2007. PMID: 17562736
In vitro screening for population variability in chemical toxicity.
O'Shea SH, Schwarz J, Kosyk O, Ross PK, Ha MJ, Wright FA, Rusyn I. O'Shea SH, et al. Among authors: kosyk o. Toxicol Sci. 2011 Feb;119(2):398-407. doi: 10.1093/toxsci/kfq322. Epub 2010 Oct 15. Toxicol Sci. 2011. PMID: 20952501 Free PMC article.
Acetaminophen-induced acute liver injury in HCV transgenic mice.
Uehara T, Kosyk O, Jeannot E, Bradford BU, Tech K, Macdonald JM, Boorman GA, Chatterjee S, Mason RP, Melnyk SB, Tryndyak VP, Pogribny IP, Rusyn I. Uehara T, et al. Among authors: kosyk o. Toxicol Appl Pharmacol. 2013 Jan 15;266(2):224-32. doi: 10.1016/j.taap.2012.11.019. Epub 2012 Nov 29. Toxicol Appl Pharmacol. 2013. PMID: 23200774 Free PMC article.
Evaluation of an in vitro toxicogenetic mouse model for hepatotoxicity.
Martinez SM, Bradford BU, Soldatow VY, Kosyk O, Sandot A, Witek R, Kaiser R, Stewart T, Amaral K, Freeman K, Black C, LeCluyse EL, Ferguson SS, Rusyn I. Martinez SM, et al. Among authors: kosyk o. Toxicol Appl Pharmacol. 2010 Dec 15;249(3):208-16. doi: 10.1016/j.taap.2010.09.012. Epub 2010 Sep 24. Toxicol Appl Pharmacol. 2010. PMID: 20869979 Free PMC article.
47 results