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Page 1
Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974).
Sinclair SR, Kane SA, Van der Schueren BJ, Xiao A, Willson KJ, Boyle J, de Lepeleire I, Xu Y, Hickey L, Denney WS, Li CC, Palcza J, Vanmolkot FH, Depré M, Van Hecken A, Murphy MG, Ho TW, de Hoon JN. Sinclair SR, et al. Br J Clin Pharmacol. 2010 Jan;69(1):15-22. doi: 10.1111/j.1365-2125.2009.03543.x. Br J Clin Pharmacol. 2010. PMID: 20078608 Free PMC article. Clinical Trial.
Calcitonin gene-related peptide8-37 antagonizes capsaicin-induced vasodilation in the skin: evaluation of a human in vivo pharmacodynamic model.
Van der Schueren BJ, Rogiers A, Vanmolkot FH, Van Hecken A, Depré M, Kane SA, De Lepeleire I, Sinclair SR, de Hoon JN. Van der Schueren BJ, et al. Among authors: sinclair sr. J Pharmacol Exp Ther. 2008 Apr;325(1):248-55. doi: 10.1124/jpet.107.133868. Epub 2008 Jan 23. J Pharmacol Exp Ther. 2008. PMID: 18216286 Clinical Trial.
Single- and multiple-dose pharmacokinetics and tolerability of telcagepant, an oral calcitonin gene-related peptide receptor antagonist, in adults.
Han TH, Blanchard RL, Palcza J, McCrea JB, Laethem T, Willson K, Xu Y, Ermlich S, Boyle J, Lines C, Gutierrez M, Van Bortel L, Xiao AJ, Sinclair S, Hickey L, Panebianco D, Murphy MG. Han TH, et al. J Clin Pharmacol. 2010 Dec;50(12):1367-76. doi: 10.1177/0091270010361741. Epub 2010 Feb 19. J Clin Pharmacol. 2010. PMID: 20173082 Clinical Trial.
Normal and pathological dynamics of platelets in humans.
Langlois GP, Craig M, Humphries AR, Mackey MC, Mahaffy JM, Bélair J, Moulin T, Sinclair SR, Wang L. Langlois GP, et al. Among authors: sinclair sr. J Math Biol. 2017 Dec;75(6-7):1411-1462. doi: 10.1007/s00285-017-1125-6. Epub 2017 Apr 8. J Math Biol. 2017. PMID: 28391511
A glial cell line-derived neurotrophic factor-secreting clone of the Schwann cell line SCTM41 enhances survival and fiber outgrowth from embryonic nigral neurons grafted to the striatum and to the lesioned substantia nigra.
Wilby MJ, Sinclair SR, Muir EM, Zietlow R, Adcock KH, Horellou P, Rogers JH, Dunnett SB, Fawcett JW. Wilby MJ, et al. Among authors: sinclair sr. J Neurosci. 1999 Mar 15;19(6):2301-12. doi: 10.1523/JNEUROSCI.19-06-02301.1999. J Neurosci. 1999. PMID: 10066280 Free PMC article.