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The novel 2Fe-2S outer mitochondrial protein mitoNEET displays conformational flexibility in its N-terminal cytoplasmic tethering domain.
Conlan AR, Paddock ML, Axelrod HL, Cohen AE, Abresch EC, Wiley S, Roy M, Nechushtai R, Jennings PA. Conlan AR, et al. Among authors: nechushtai r. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jul 1;65(Pt 7):654-9. doi: 10.1107/S1744309109019605. Epub 2009 Jun 27. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19574633 Free PMC article.
Mutation of the His ligand in mitoNEET stabilizes the 2Fe-2S cluster despite conformational heterogeneity in the ligand environment.
Conlan AR, Paddock ML, Homer C, Axelrod HL, Cohen AE, Abresch EC, Zuris JA, Nechushtai R, Jennings PA. Conlan AR, et al. Among authors: nechushtai r. Acta Crystallogr D Biol Crystallogr. 2011 Jun;67(Pt 6):516-23. doi: 10.1107/S0907444911011577. Epub 2011 May 17. Acta Crystallogr D Biol Crystallogr. 2011. PMID: 21636891 Free PMC article.
Facile transfer of [2Fe-2S] clusters from the diabetes drug target mitoNEET to an apo-acceptor protein.
Zuris JA, Harir Y, Conlan AR, Shvartsman M, Michaeli D, Tamir S, Paddock ML, Onuchic JN, Mittler R, Cabantchik ZI, Jennings PA, Nechushtai R. Zuris JA, et al. Among authors: nechushtai r. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13047-52. doi: 10.1073/pnas.1109986108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788481 Free PMC article.
129 results