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Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1.
Johnen H, Lin S, Kuffner T, Brown DA, Tsai VW, Bauskin AR, Wu L, Pankhurst G, Jiang L, Junankar S, Hunter M, Fairlie WD, Lee NJ, Enriquez RF, Baldock PA, Corey E, Apple FS, Murakami MM, Lin EJ, Wang C, During MJ, Sainsbury A, Herzog H, Breit SN. Johnen H, et al. Among authors: herzog h. Nat Med. 2007 Nov;13(11):1333-40. doi: 10.1038/nm1677. Epub 2007 Nov 4. Nat Med. 2007. PMID: 17982462
Gut hormone PYY(3-36) physiologically inhibits food intake.
Batterham RL, Cowley MA, Small CJ, Herzog H, Cohen MA, Dakin CL, Wren AM, Brynes AE, Low MJ, Ghatei MA, Cone RD, Bloom SR. Batterham RL, et al. Among authors: herzog h. Nature. 2002 Aug 8;418(6898):650-4. doi: 10.1038/nature00887. Nature. 2002. PMID: 12167864
Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity.
Yan C, Zeng T, Lee K, Nobis M, Loh K, Gou L, Xia Z, Gao Z, Bensellam M, Hughes W, Lau J, Zhang L, Ip CK, Enriquez R, Gao H, Wang QP, Wu Q, Haigh JJ, Laybutt DR, Timpson P, Herzog H, Shi YC. Yan C, et al. Among authors: herzog h. Nat Commun. 2021 May 11;12(1):2622. doi: 10.1038/s41467-021-22925-3. Nat Commun. 2021. PMID: 33976180 Free PMC article.
Peripheral-specific y2 receptor knockdown protects mice from high-fat diet-induced obesity.
Shi YC, Lin S, Castillo L, Aljanova A, Enriquez RF, Nguyen AD, Baldock PA, Zhang L, Bijker MS, Macia L, Yulyaningsih E, Zhang H, Lau J, Sainsbury A, Herzog H. Shi YC, et al. Among authors: herzog h. Obesity (Silver Spring). 2011 Nov;19(11):2137-48. doi: 10.1038/oby.2011.99. Epub 2011 May 5. Obesity (Silver Spring). 2011. PMID: 21546930 Free article.
806 results