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Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function.
Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Jensen E, Imitola J, Korn T, Anderson AC, Zhang Z, Gutierrez C, Moll T, Sobel RA, Umetsu DT, Yagita H, Akiba H, Strom T, Sayegh MH, DeKruyff RH, Khoury SJ, Kuchroo VK. Xiao S, et al. Among authors: dekruyff rh. J Exp Med. 2007 Jul 9;204(7):1691-702. doi: 10.1084/jem.20062498. Epub 2007 Jul 2. J Exp Med. 2007. PMID: 17606630 Free PMC article.
The costimulatory role of TIM molecules.
Rodriguez-Manzanet R, DeKruyff R, Kuchroo VK, Umetsu DT. Rodriguez-Manzanet R, et al. Immunol Rev. 2009 May;229(1):259-70. doi: 10.1111/j.1600-065X.2009.00772.x. Immunol Rev. 2009. PMID: 19426227 Free PMC article. Review.
TIM family of genes in immunity and tolerance.
Kuchroo VK, Meyers JH, Umetsu DT, DeKruyff RH. Kuchroo VK, et al. Among authors: dekruyff rh. Adv Immunol. 2006;91:227-49. doi: 10.1016/S0065-2776(06)91006-2. Adv Immunol. 2006. PMID: 16938542 Review.
186 results