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Page 1
Tuberculosis.
Pai M, Behr MA, Dowdy D, Dheda K, Divangahi M, Boehme CC, Ginsberg A, Swaminathan S, Spigelman M, Getahun H, Menzies D, Raviglione M. Pai M, et al. Nat Rev Dis Primers. 2016 Oct 27;2:16076. doi: 10.1038/nrdp.2016.76. Nat Rev Dis Primers. 2016. PMID: 27784885 Review.
Analysis of the clinical antibacterial and antituberculosis pipeline.
Theuretzbacher U, Gottwalt S, Beyer P, Butler M, Czaplewski L, Lienhardt C, Moja L, Paul M, Paulin S, Rex JH, Silver LL, Spigelman M, Thwaites GE, Paccaud JP, Harbarth S. Theuretzbacher U, et al. Lancet Infect Dis. 2019 Feb;19(2):e40-e50. doi: 10.1016/S1473-3099(18)30513-9. Epub 2018 Oct 15. Lancet Infect Dis. 2019. PMID: 30337260
Novel targets for tuberculosis drug discovery.
Mdluli K, Spigelman M. Mdluli K, et al. Curr Opin Pharmacol. 2006 Oct;6(5):459-67. doi: 10.1016/j.coph.2006.06.004. Epub 2006 Aug 9. Curr Opin Pharmacol. 2006. PMID: 16904376 Review.
Safety, tolerability, and pharmacokinetics of PA-824 in healthy subjects.
Ginsberg AM, Laurenzi MW, Rouse DJ, Whitney KD, Spigelman MK. Ginsberg AM, et al. Among authors: spigelman mk. Antimicrob Agents Chemother. 2009 Sep;53(9):3720-5. doi: 10.1128/AAC.00106-09. Epub 2009 Jun 15. Antimicrob Agents Chemother. 2009. PMID: 19528280 Free PMC article. Clinical Trial.
Efficiency and safety of the combination of moxifloxacin, pretomanid (PA-824), and pyrazinamide during the first 8 weeks of antituberculosis treatment: a phase 2b, open-label, partly randomised trial in patients with drug-susceptible or drug-resistant pulmonary tuberculosis.
Dawson R, Diacon AH, Everitt D, van Niekerk C, Donald PR, Burger DA, Schall R, Spigelman M, Conradie A, Eisenach K, Venter A, Ive P, Page-Shipp L, Variava E, Reither K, Ntinginya NE, Pym A, von Groote-Bidlingmaier F, Mendel CM. Dawson R, et al. Lancet. 2015 May 2;385(9979):1738-1747. doi: 10.1016/S0140-6736(14)62002-X. Epub 2015 Mar 18. Lancet. 2015. PMID: 25795076 Clinical Trial.
50 results