Avlani VA - Search Results

1

Involvement of the sigma1 (sigma1) receptor in the anti-amnesic, but not antidepressant-like, effects of the aminotetrahydrofuran derivative ANAVEX1-41.

Espallergues J, Lapalud P, Christopoulos A, Avlani VA, Sexton PM, Vamvakides A, Maurice T. Espallergues J, et al. Among authors: avlani va. Br J Pharmacol. 2007 Sep;152(2):267-79. doi: 10.1038/sj.bjp.0707386. Epub 2007 Aug 6. Br J Pharmacol. 2007. PMID: 17641675 Free PMC article.

2

Application of a kinetic model to the apparently complex behavior of negative and positive allosteric modulators of muscarinic acetylcholine receptors.

Avlani V, May LT, Sexton PM, Christopoulos A. Avlani V, et al. J Pharmacol Exp Ther. 2004 Mar;308(3):1062-72. doi: 10.1124/jpet.103.059840. Epub 2004 Jan 7. J Pharmacol Exp Ther. 2004. PMID: 14711931

3

Orthosteric and allosteric modes of interaction of novel selective agonists of the M1 muscarinic acetylcholine receptor.

Avlani VA, Langmead CJ, Guida E, Wood MD, Tehan BG, Herdon HJ, Watson JM, Sexton PM, Christopoulos A. Avlani VA, et al. Mol Pharmacol. 2010 Jul;78(1):94-104. doi: 10.1124/mol.110.064345. Epub 2010 Apr 22. Mol Pharmacol. 2010. PMID: 20413650

4

Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors.

May LT, Avlani VA, Langmead CJ, Herdon HJ, Wood MD, Sexton PM, Christopoulos A. May LT, et al. Among authors: avlani va. Mol Pharmacol. 2007 Aug;72(2):463-76. doi: 10.1124/mol.107.037630. Epub 2007 May 24. Mol Pharmacol. 2007. PMID: 17525129

5

The impact of orthosteric radioligand depletion on the quantification of allosteric modulator interactions.

Avlani VA, McLoughlin DJ, Sexton PM, Christopoulos A. Avlani VA, et al. J Pharmacol Exp Ther. 2008 Jun;325(3):927-34. doi: 10.1124/jpet.108.136978. Epub 2008 Mar 5. J Pharmacol Exp Ther. 2008. PMID: 18322151

6

Allosteric modulation of G protein-coupled receptors.

May LT, Avlani VA, Sexton PM, Christopoulos A. May LT, et al. Among authors: avlani va. Curr Pharm Des. 2004;10(17):2003-13. doi: 10.2174/1381612043384303. Curr Pharm Des. 2004. PMID: 15279541 Review.

7

G-protein-coupled receptor allosterism: the promise and the problem(s).

Christopoulos A, May LT, Avlani VA, Sexton PM. Christopoulos A, et al. Among authors: avlani va. Biochem Soc Trans. 2004 Nov;32(Pt 5):873-7. doi: 10.1042/BST0320873. Biochem Soc Trans. 2004. PMID: 15494038 Review.

8

Critical role for the second extracellular loop in the binding of both orthosteric and allosteric G protein-coupled receptor ligands.

Avlani VA, Gregory KJ, Morton CJ, Parker MW, Sexton PM, Christopoulos A. Avlani VA, et al. J Biol Chem. 2007 Aug 31;282(35):25677-86. doi: 10.1074/jbc.M702311200. Epub 2007 Jun 25. J Biol Chem. 2007. PMID: 17591774 Free article.

9

Calcium-sensing receptor-dependent activation of CREB phosphorylation in HEK293 cells and human parathyroid cells.

Avlani VA, Ma W, Mun HC, Leach K, Delbridge L, Christopoulos A, Conigrave AD. Avlani VA, et al. Am J Physiol Endocrinol Metab. 2013 May 15;304(10):E1097-104. doi: 10.1152/ajpendo.00054.2013. Epub 2013 Mar 26. Am J Physiol Endocrinol Metab. 2013. PMID: 23531616 Free article.

10

Roles of intraloops-2 and -3 and the proximal C-terminus in signalling pathway selection from the human calcium-sensing receptor.

Goolam MA, Ward JH, Avlani VA, Leach K, Christopoulos A, Conigrave AD. Goolam MA, et al. Among authors: avlani va. FEBS Lett. 2014 Sep 17;588(18):3340-6. doi: 10.1016/j.febslet.2014.07.022. Epub 2014 Jul 28. FEBS Lett. 2014. PMID: 25080008 Free article.

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