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Serotonin transporter mutations associated with obsessive-compulsive disorder and phosphorylation alter binding affinity for inhibitors.
Zhang YW, Rudnick G. Zhang YW, et al. Among authors: rudnick g. Neuropharmacology. 2005 Nov;49(6):791-7. doi: 10.1016/j.neuropharm.2005.06.019. Epub 2005 Aug 19. Neuropharmacology. 2005. PMID: 16112691
Mutation at Ile-425 to valine, found in some patients with obsessive-compulsive disorder, altered the response of SERT to cGMP (Kilic, F., Murphy, D.L., Rudnick, G., 2003. A human serotonin transporter mutation causes constitutive activation of transport activity. . …
Mutation at Ile-425 to valine, found in some patients with obsessive-compulsive disorder, altered the response of SERT to cGMP (Kilic, F., M …
Mechanism for alternating access in neurotransmitter transporters.
Forrest LR, Zhang YW, Jacobs MT, Gesmonde J, Xie L, Honig BH, Rudnick G. Forrest LR, et al. Among authors: rudnick g. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10338-43. doi: 10.1073/pnas.0804659105. Epub 2008 Jul 22. Proc Natl Acad Sci U S A. 2008. PMID: 18647834 Free PMC article.
131 results