Dambach DM - Search Results

1

A retrospective analysis of toxicogenomics in the safety assessment of drug candidates.

Foster WR, Chen SJ, He A, Truong A, Bhaskaran V, Nelson DM, Dambach DM, Lehman-McKeeman LD, Car BD. Foster WR, et al. Among authors: dambach dm. Toxicol Pathol. 2007 Aug;35(5):621-35. doi: 10.1080/01926230701419063. Toxicol Pathol. 2007. PMID: 17654404 Review.

2

New technologies and screening strategies for hepatotoxicity: use of in vitro models.

Dambach DM, Andrews BA, Moulin F. Dambach DM, et al. Toxicol Pathol. 2005;33(1):17-26. doi: 10.1080/01926230590522284. Toxicol Pathol. 2005. PMID: 15805052 Review.

3

Cloning, expression and characterization of monkey (Macaca fascicularis) CD137.

Chen SJ, Foster WR, Jure-Kunkel MN, Girit E, Abraham R, Hefta LJ, Gao S, Yonan CR, Lin JH, Dambach DM. Chen SJ, et al. Among authors: dambach dm. Vet Immunol Immunopathol. 2008 Dec 15;126(3-4):377-81. doi: 10.1016/j.vetimm.2008.07.009. Epub 2008 Jul 31. Vet Immunol Immunopathol. 2008. PMID: 18771806

4

Integrated risk assessment of suicidal ideation and behavior in drug development.

Muller PY, Dambach D, Gemzik B, Hartmann A, Ratcliffe S, Trendelenburg C, Urban L. Muller PY, et al. Drug Discov Today. 2015 Sep;20(9):1135-42. doi: 10.1016/j.drudis.2015.05.010. Epub 2015 May 27. Drug Discov Today. 2015. PMID: 26022402 Review.

5

Identification of in vitro protein biomarkers of idiosyncratic liver toxicity.

Gao J, Ann Garulacan L, Storm SM, Hefta SA, Opiteck GJ, Lin JH, Moulin F, Dambach DM. Gao J, et al. Among authors: dambach dm. Toxicol In Vitro. 2004 Aug;18(4):533-41. doi: 10.1016/j.tiv.2004.01.012. Toxicol In Vitro. 2004. PMID: 15130611

6

MEK and ERK Kinase Inhibitors Increase Circulating Ceruloplasmin and Cause Green Serum in Rats.

Diaz D, Pai R, Cain G, La N, Dambach D, Schwartz J, Tarrant JM. Diaz D, et al. Toxicol Pathol. 2017 Feb;45(2):353-361. doi: 10.1177/0192623316664590. Epub 2016 Sep 28. Toxicol Pathol. 2017. PMID: 27565173

7

Biomarker discovery in biological fluids.

Gao J, Garulacan LA, Storm SM, Opiteck GJ, Dubaquie Y, Hefta SA, Dambach DM, Dongre AR. Gao J, et al. Among authors: dambach dm. Methods. 2005 Mar;35(3):291-302. doi: 10.1016/j.ymeth.2004.08.020. Epub 2005 Jan 12. Methods. 2005. PMID: 15722225

8

Potential adverse effects associated with inhibition of p38alpha/beta MAP kinases.

Dambach DM. Dambach DM. Curr Top Med Chem. 2005;5(10):929-39. doi: 10.2174/1568026054985911. Curr Top Med Chem. 2005. PMID: 16178738 Review.

9

Current nonclinical testing paradigm enables safe entry to First-In-Human clinical trials: The IQ consortium nonclinical to clinical translational database.

Monticello TM, Jones TW, Dambach DM, Potter DM, Bolt MW, Liu M, Keller DA, Hart TK, Kadambi VJ. Monticello TM, et al. Among authors: dambach dm. Toxicol Appl Pharmacol. 2017 Nov 1;334:100-109. doi: 10.1016/j.taap.2017.09.006. Epub 2017 Sep 8. Toxicol Appl Pharmacol. 2017. PMID: 28893587

10

Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase: discovery and SAR leading to the identification of N-(2-(6-(4-ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419).

Watterson SH, Chen P, Zhao Y, Gu HH, Dhar TG, Xiao Z, Ballentine SK, Shen Z, Fleener CA, Rouleau KA, Obermeier M, Yang Z, McIntyre KW, Shuster DJ, Witmer M, Dambach D, Chao S, Mathur A, Chen BC, Barrish JC, Robl JA, Townsend R, Iwanowicz EJ. Watterson SH, et al. J Med Chem. 2007 Jul 26;50(15):3730-42. doi: 10.1021/jm070299x. Epub 2007 Jun 22. J Med Chem. 2007. PMID: 17585753

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