Nelson DM - Search Results

1

A retrospective analysis of toxicogenomics in the safety assessment of drug candidates.

Foster WR, Chen SJ, He A, Truong A, Bhaskaran V, Nelson DM, Dambach DM, Lehman-McKeeman LD, Car BD. Foster WR, et al. Among authors: nelson dm. Toxicol Pathol. 2007 Aug;35(5):621-35. doi: 10.1080/01926230701419063. Toxicol Pathol. 2007. PMID: 17654404 Review.

2

p53-independent induction of rat hepatic Mdm2 following administration of phenobarbital and pregnenolone 16alpha-carbonitrile.

Nelson DM, Bhaskaran V, Foster WR, Lehman-McKeeman LD. Nelson DM, et al. Toxicol Sci. 2006 Dec;94(2):272-80. doi: 10.1093/toxsci/kfl115. Epub 2006 Sep 25. Toxicol Sci. 2006. PMID: 17000718

3

Modulation of ascorbic acid metabolism by cytochrome P450 induction revealed by metabonomics and transcriptional profiling.

Aranibar N, Bhaskaran V, Ott KH, Vassallo J, Nelson D, Lecureux L, Gong L, Stryker S, Lehman-McKeeman L. Aranibar N, et al. Magn Reson Chem. 2009 Dec;47 Suppl 1:S12-9. doi: 10.1002/mrc.2503. Magn Reson Chem. 2009. PMID: 19768707

4

Evidence for the involvement of xenobiotic-responsive nuclear receptors in transcriptional effects upon perfluoroalkyl acid exposure in diverse species.

Ren H, Vallanat B, Nelson DM, Yeung LWY, Guruge KS, Lam PKS, Lehman-McKeeman LD, Corton JC. Ren H, et al. Among authors: nelson dm. Reprod Toxicol. 2009 Jun;27(3-4):266-277. doi: 10.1016/j.reprotox.2008.12.011. Epub 2009 Jan 3. Reprod Toxicol. 2009. PMID: 19162173

5

Hepatobiliary disposition of thyroid hormone in Mrp2-deficient TR- rats: reduced biliary excretion of thyroxine glucuronide does not prevent xenobiotic-induced hypothyroidism.

Lecureux L, Dieter MZ, Nelson DM, Watson L, Wong H, Gemzik B, Klaassen CD, Lehman-McKeeman LD. Lecureux L, et al. Among authors: nelson dm. Toxicol Sci. 2009 Apr;108(2):482-91. doi: 10.1093/toxsci/kfp026. Epub 2009 Feb 11. Toxicol Sci. 2009. PMID: 19211616

6

Unique gene expression and hepatocellular injury in the lipopolysaccharide-ranitidine drug idiosyncrasy rat model: comparison with famotidine.

Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Reilly TP, Car BD, Cantor GH, Maddox JF, Ganey PE, Roth RA. Luyendyk JP, et al. Among authors: nelson dm. Toxicol Sci. 2006 Apr;90(2):569-85. doi: 10.1093/toxsci/kfj103. Epub 2006 Jan 16. Toxicol Sci. 2006. PMID: 16415329

7

Coagulation-dependent gene expression and liver injury in rats given lipopolysaccharide with ranitidine but not with famotidine.

Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Reilly TP, Car BD, Cantor GH, Deng X, Maddox JF, Ganey PE, Roth RA. Luyendyk JP, et al. Among authors: nelson dm. J Pharmacol Exp Ther. 2006 May;317(2):635-43. doi: 10.1124/jpet.105.096305. Epub 2006 Jan 9. J Pharmacol Exp Ther. 2006. PMID: 16401727

8

Comparison of TNFα to lipopolysaccharide as an inflammagen to characterize the idiosyncratic hepatotoxicity potential of drugs: Trovafloxacin as an example.

Liguori MJ, Ditewig AC, Maddox JF, Luyendyk JP, Lehman-McKeeman LD, Nelson DM, Bhaskaran VM, Waring JF, Ganey PE, Roth RA, Blomme EA. Liguori MJ, et al. Among authors: nelson dm. Int J Mol Sci. 2010 Nov 18;11(11):4697-714. doi: 10.3390/ijms11114697. Int J Mol Sci. 2010. PMID: 21151465 Free PMC article.

9

Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2.

Fisher CD, Augustine LM, Maher JM, Nelson DM, Slitt AL, Klaassen CD, Lehman-McKeeman LD, Cherrington NJ. Fisher CD, et al. Among authors: nelson dm. Drug Metab Dispos. 2007 Jun;35(6):995-1000. doi: 10.1124/dmd.106.014340. Epub 2007 Mar 12. Drug Metab Dispos. 2007. PMID: 17353348

10

Calcified left ventricular apical aneurysm with intramural thrombus: a case report.

Nelson DM, Brennan AP, Raman J, Burns AT. Nelson DM, et al. Eur Heart J Case Rep. 2024 Mar 20;8(4):ytae143. doi: 10.1093/ehjcr/ytae143. eCollection 2024 Apr. Eur Heart J Case Rep. 2024. PMID: 38567276 Free PMC article.

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