Paeshuyse J - Search Results

1

Antiviral 2,5-disubstituted imidazo[4,5-c]pyridines: further optimization of anti-hepatitis C virus activity.

Puerstinger G, Paeshuyse J, Heinrich S, Mohr J, Schraffl N, De Clercq E, Neyts J. Puerstinger G, et al. Among authors: paeshuyse j. Bioorg Med Chem Lett. 2007 Sep 15;17(18):5111-4. doi: 10.1016/j.bmcl.2007.07.015. Epub 2007 Jul 13. Bioorg Med Chem Lett. 2007. PMID: 17656093

2

Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines: a new class of pestivirus inhibitors.

Puerstinger G, Paeshuyse J, Herdewijn P, Rozenski J, De Clercq E, Neyts J. Puerstinger G, et al. Among authors: paeshuyse j. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5345-9. doi: 10.1016/j.bmcl.2006.07.081. Epub 2006 Aug 9. Bioorg Med Chem Lett. 2006. PMID: 16901692

3

Antiviral 2,5-disubstituted imidazo[4,5-c]pyridines: from anti-pestivirus to anti-hepatitis C virus activity.

Puerstinger G, Paeshuyse J, De Clercq E, Neyts J. Puerstinger G, et al. Among authors: paeshuyse j. Bioorg Med Chem Lett. 2007 Jan 15;17(2):390-3. doi: 10.1016/j.bmcl.2006.10.039. Epub 2006 Oct 19. Bioorg Med Chem Lett. 2007. PMID: 17084081

4

Imidazo[4,5-c]pyridines inhibit the in vitro replication of the classical swine fever virus and target the viral polymerase.

Vrancken R, Paeshuyse J, Haegeman A, Puerstinger G, Froeyen M, Herdewijn P, Kerkhofs P, Neyts J, Koenen F. Vrancken R, et al. Among authors: paeshuyse j. Antiviral Res. 2008 Feb;77(2):114-9. doi: 10.1016/j.antiviral.2007.09.006. Epub 2007 Oct 22. Antiviral Res. 2008. PMID: 17997169 Free article.

5

Synthesis and anti-BVDV activity of acridones as new potential antiviral agents.

Tabarrini O, Manfroni G, Fravolini A, Cecchetti V, Sabatini S, De Clercq E, Rozenski J, Canard B, Dutartre H, Paeshuyse J, Neyts J. Tabarrini O, et al. Among authors: paeshuyse j. J Med Chem. 2006 Apr 20;49(8):2621-7. doi: 10.1021/jm051250z. J Med Chem. 2006. PMID: 16610805

6

Ribavirin antagonizes the in vitro anti-hepatitis C virus activity of 2'-C-methylcytidine, the active component of valopicitabine.

Coelmont L, Paeshuyse J, Windisch MP, De Clercq E, Bartenschlager R, Neyts J. Coelmont L, et al. Among authors: paeshuyse j. Antimicrob Agents Chemother. 2006 Oct;50(10):3444-6. doi: 10.1128/AAC.00372-06. Antimicrob Agents Chemother. 2006. PMID: 17005827 Free PMC article.

7

Proof of concept for the reduction of classical swine fever infection in pigs by a novel viral polymerase inhibitor.

Vrancken R, Haegeman A, Paeshuyse J, Puerstinger G, Rozenski J, Wright M, Tignon M, Le Potier MF, Neyts J, Koenen F. Vrancken R, et al. Among authors: paeshuyse j. J Gen Virol. 2009 Jun;90(Pt 6):1335-1342. doi: 10.1099/vir.0.008839-0. Epub 2009 Mar 4. J Gen Virol. 2009. PMID: 19264669

8

Synthesis and antiviral activity of an imidazo[1,2-a]pyrrolo[2,3-c]pyridine series against the bovine viral diarrhea virus.

Chezal JM, Paeshuyse J, Gaumet V, Canitrot D, Maisonial A, Lartigue C, Gueiffier A, Moreau E, Teulade JC, Chavignon O, Neyts J. Chezal JM, et al. Among authors: paeshuyse j. Eur J Med Chem. 2010 May;45(5):2044-7. doi: 10.1016/j.ejmech.2010.01.023. Epub 2010 Jan 20. Eur J Med Chem. 2010. PMID: 20149501

9

3-Biphenylimidazo[1,2-a]pyridines or [1,2-b]pyridazines and analogues, novel Flaviviridae inhibitors.

Enguehard-Gueiffier C, Musiu S, Henry N, Véron JB, Mavel S, Neyts J, Leyssen P, Paeshuyse J, Gueiffier A. Enguehard-Gueiffier C, et al. Among authors: paeshuyse j. Eur J Med Chem. 2013 Jun;64:448-63. doi: 10.1016/j.ejmech.2013.03.054. Epub 2013 Apr 19. Eur J Med Chem. 2013. PMID: 23665801

10

Substituted 2,6-bis(benzimidazol-2-yl)pyridines: a novel chemical class of pestivirus inhibitors that targets a hot spot for inhibition of pestivirus replication in the RNA-dependent RNA polymerase.

Musiu S, Pürstinger G, Stallinger S, Vrancken R, Haegeman A, Koenen F, Leyssen P, Froeyen M, Neyts J, Paeshuyse J. Musiu S, et al. Among authors: paeshuyse j. Antiviral Res. 2014 Jun;106:71-9. doi: 10.1016/j.antiviral.2014.03.010. Epub 2014 Mar 27. Antiviral Res. 2014. PMID: 24680957

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