Hodek P - Search Results

1

The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolism.

Aimová D, Svobodová L, Kotrbová V, Mrázová B, Hodek P, Hudecek J, Václavíková R, Frei E, Stiborová M. Aimová D, et al. Among authors: hodek p. Drug Metab Dispos. 2007 Oct;35(10):1926-34. doi: 10.1124/dmd.107.016048. Epub 2007 Jul 26. Drug Metab Dispos. 2007. PMID: 17656468

2

Metabolism of diamantane by rat liver microsomal cytochromes P-450.

Hodek P, Janscák P, Anzenbacher P, Burkhard J, Janků J, Vodicka L. Hodek P, et al. Xenobiotica. 1988 Oct;18(10):1109-18. doi: 10.3109/00498258809042233. Xenobiotica. 1988. PMID: 3242307

3

The first identification of the benzenediazonium ion formation from a non-aminoazo dye, 1-phenylazo-2-hydroxynaphthalene (Sudan I) by microsomes of rat livers.

Stiborová M, Asfaw B, Anzenbacher P, Leseticky L, Hodek P. Stiborová M, et al. Among authors: hodek p. Cancer Lett. 1988 Jun 30;40(3):319-26. doi: 10.1016/0304-3835(88)90091-2. Cancer Lett. 1988. PMID: 3383183

4

A new way to carcinogenicity of azo dyes: the benzenediazonium ion formed from a non-aminoazo dye, 1-phenylazo-2-hydroxynaphthalene(Sudan I) by microsomal enzymes binds to deoxyguanosine residues of DNA.

Stiborová M, Asfaw B, Anzenbacher P, Hodek P. Stiborová M, et al. Among authors: hodek p. Cancer Lett. 1988 Jun 30;40(3):327-33. doi: 10.1016/0304-3835(88)90092-4. Cancer Lett. 1988. PMID: 3383184

5

alpha-Naphthoflavone acts as activator and reversible or irreversible inhibitor of rabbit microsomal CYP3A6.

Boek-Dohalská L, Hodek P, Sulc M, Stiborová M. Boek-Dohalská L, et al. Among authors: hodek p. Chem Biol Interact. 2001 Oct 25;138(1):85-106. doi: 10.1016/s0009-2797(01)00263-0. Chem Biol Interact. 2001. PMID: 11640917

6

Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450.

Hodek P, Trefil P, Stiborová M. Hodek P, et al. Chem Biol Interact. 2002 Jan 22;139(1):1-21. doi: 10.1016/s0009-2797(01)00285-x. Chem Biol Interact. 2002. PMID: 11803026 Review.

7

New selective inhibitors of cytochromes P450 2B and their application to antimutagenesis of tamoxifen.

Stiborová M, Borek-Dohalská L, Hodek P, Mráz J, Frei E. Stiborová M, et al. Among authors: hodek p. Arch Biochem Biophys. 2002 Jul 1;403(1):41-9. doi: 10.1016/S0003-9861(02)00259-X. Arch Biochem Biophys. 2002. PMID: 12061800

8

Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes.

Stiborová M, Martínek V, Rýdlová H, Hodek P, Frei E. Stiborová M, et al. Among authors: hodek p. Cancer Res. 2002 Oct 15;62(20):5678-84. Cancer Res. 2002. PMID: 12384524

9

Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.

Stiborová M, Frei E, Hodek P, Wiessler M, Schmeiser HH. Stiborová M, et al. Among authors: hodek p. Int J Cancer. 2005 Jan 10;113(2):189-97. doi: 10.1002/ijc.20564. Int J Cancer. 2005. PMID: 15386410

10

Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers.

Stiborová M, Martínek V, Rýdlová H, Koblas T, Hodek P. Stiborová M, et al. Among authors: hodek p. Cancer Lett. 2005 Apr 8;220(2):145-54. doi: 10.1016/j.canlet.2004.07.036. Cancer Lett. 2005. PMID: 15766589

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