Lynch AG - Search Results

1

Numbers of copy-number variations and false-negative rates will be underestimated if we do not account for the dependence between repeated experiments.

Lynch AG, Marioni JC, Tavaré S. Lynch AG, et al. Am J Hum Genet. 2007 Aug;81(2):418-20; author reply 420-1. doi: 10.1086/519393. Am J Hum Genet. 2007. PMID: 17668395 Free PMC article. No abstract available.

2

Breaking the waves: improved detection of copy number variation from microarray-based comparative genomic hybridization.

Marioni JC, Thorne NP, Valsesia A, Fitzgerald T, Redon R, Fiegler H, Andrews TD, Stranger BE, Lynch AG, Dermitzakis ET, Carter NP, Tavaré S, Hurles ME. Marioni JC, et al. Among authors: lynch ag. Genome Biol. 2007;8(10):R228. doi: 10.1186/gb-2007-8-10-r228. Genome Biol. 2007. PMID: 17961237 Free PMC article.

3

Hidden copy number variation in the HapMap population.

Marioni JC, White M, Tavaré S, Lynch AG. Marioni JC, et al. Among authors: lynch ag. Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10067-72. doi: 10.1073/pnas.0711252105. Epub 2008 Jul 15. Proc Natl Acad Sci U S A. 2008. PMID: 18632583 Free PMC article.

4

The pitfalls of platform comparison: DNA copy number array technologies assessed.

Curtis C, Lynch AG, Dunning MJ, Spiteri I, Marioni JC, Hadfield J, Chin SF, Brenton JD, Tavaré S, Caldas C. Curtis C, et al. Among authors: lynch ag. BMC Genomics. 2009 Dec 8;10:588. doi: 10.1186/1471-2164-10-588. BMC Genomics. 2009. PMID: 19995423 Free PMC article.

5

Statistical issues in the analysis of Illumina data.

Dunning MJ, Barbosa-Morais NL, Lynch AG, Tavaré S, Ritchie ME. Dunning MJ, et al. Among authors: lynch ag. BMC Bioinformatics. 2008 Feb 6;9:85. doi: 10.1186/1471-2105-9-85. BMC Bioinformatics. 2008. PMID: 18254947 Free PMC article.

6

The cost of reducing starting RNA quantity for Illumina BeadArrays: a bead-level dilution experiment.

Lynch AG, Hadfield J, Dunning MJ, Osborne M, Thorne NP, Tavaré S. Lynch AG, et al. BMC Genomics. 2010 Oct 6;11:540. doi: 10.1186/1471-2164-11-540. BMC Genomics. 2010. PMID: 20925945 Free PMC article.

7

Quantifying the impact of inter-site heterogeneity on the distribution of ChIP-seq data.

Cairns J, Lynch AG, Tavaré S. Cairns J, et al. Among authors: lynch ag. Front Genet. 2014 Nov 14;5:399. doi: 10.3389/fgene.2014.00399. eCollection 2014. Front Genet. 2014. PMID: 25452765 Free PMC article.

8

multiSNV: a probabilistic approach for improving detection of somatic point mutations from multiple related tumour samples.

Josephidou M, Lynch AG, Tavaré S. Josephidou M, et al. Among authors: lynch ag. Nucleic Acids Res. 2015 May 19;43(9):e61. doi: 10.1093/nar/gkv135. Epub 2015 Feb 26. Nucleic Acids Res. 2015. PMID: 25722372 Free PMC article.

9

Calling sample mix-ups in cancer population studies.

Lynch AG, Chin SF, Dunning MJ, Caldas C, Tavaré S, Curtis C. Lynch AG, et al. PLoS One. 2012;7(8):e41815. doi: 10.1371/journal.pone.0041815. Epub 2012 Aug 9. PLoS One. 2012. PMID: 22912679 Free PMC article.

10

Identification and correction of previously unreported spatial phenomena using raw Illumina BeadArray data.

Smith ML, Dunning MJ, Tavaré S, Lynch AG. Smith ML, et al. Among authors: lynch ag. BMC Bioinformatics. 2010 Apr 27;11:208. doi: 10.1186/1471-2105-11-208. BMC Bioinformatics. 2010. PMID: 20423502 Free PMC article.

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