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Soluble guanylate cyclase-alpha1 deficiency selectively inhibits the pulmonary vasodilator response to nitric oxide and increases the pulmonary vascular remodeling response to chronic hypoxia.
Vermeersch P, Buys E, Pokreisz P, Marsboom G, Ichinose F, Sips P, Pellens M, Gillijns H, Swinnen M, Graveline A, Collen D, Dewerchin M, Brouckaert P, Bloch KD, Janssens S. Vermeersch P, et al. Among authors: bloch kd. Circulation. 2007 Aug 21;116(8):936-43. doi: 10.1161/CIRCULATIONAHA.106.677245. Epub 2007 Aug 6. Circulation. 2007. PMID: 17679618
Cardiomyocyte-specific overexpression of nitric oxide synthase 3 improves left ventricular performance and reduces compensatory hypertrophy after myocardial infarction.
Janssens S, Pokreisz P, Schoonjans L, Pellens M, Vermeersch P, Tjwa M, Jans P, Scherrer-Crosbie M, Picard MH, Szelid Z, Gillijns H, Van de Werf F, Collen D, Bloch KD. Janssens S, et al. Among authors: bloch kd. Circ Res. 2004 May 14;94(9):1256-62. doi: 10.1161/01.RES.0000126497.38281.23. Epub 2004 Mar 25. Circ Res. 2004. PMID: 15044322 Free article.
Ventricular phosphodiesterase-5 expression is increased in patients with advanced heart failure and contributes to adverse ventricular remodeling after myocardial infarction in mice.
Pokreisz P, Vandenwijngaert S, Bito V, Van den Bergh A, Lenaerts I, Busch C, Marsboom G, Gheysens O, Vermeersch P, Biesmans L, Liu X, Gillijns H, Pellens M, Van Lommel A, Buys E, Schoonjans L, Vanhaecke J, Verbeken E, Sipido K, Herijgers P, Bloch KD, Janssens SP. Pokreisz P, et al. Among authors: bloch kd. Circulation. 2009 Jan 27;119(3):408-16. doi: 10.1161/CIRCULATIONAHA.108.822072. Epub 2009 Jan 12. Circulation. 2009. PMID: 19139381 Free PMC article.
Disruption of nitric oxide synthase 3 protects against the cardiac injury, dysfunction, and mortality induced by doxorubicin.
Neilan TG, Blake SL, Ichinose F, Raher MJ, Buys ES, Jassal DS, Furutani E, Perez-Sanz TM, Graveline A, Janssens SP, Picard MH, Scherrer-Crosbie M, Bloch KD. Neilan TG, et al. Among authors: bloch kd. Circulation. 2007 Jul 31;116(5):506-14. doi: 10.1161/CIRCULATIONAHA.106.652339. Epub 2007 Jul 16. Circulation. 2007. PMID: 17638931
Nitric oxide inhalation improves microvascular flow and decreases infarction size after myocardial ischemia and reperfusion.
Liu X, Huang Y, Pokreisz P, Vermeersch P, Marsboom G, Swinnen M, Verbeken E, Santos J, Pellens M, Gillijns H, Van de Werf F, Bloch KD, Janssens S. Liu X, et al. Among authors: bloch kd. J Am Coll Cardiol. 2007 Aug 21;50(8):808-17. doi: 10.1016/j.jacc.2007.04.069. Epub 2007 Aug 6. J Am Coll Cardiol. 2007. PMID: 17707188 Free article.
243 results