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Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors.
Kagan VE, Tyurin VA, Jiang J, Tyurina YY, Ritov VB, Amoscato AA, Osipov AN, Belikova NA, Kapralov AA, Kini V, Vlasova II, Zhao Q, Zou M, Di P, Svistunenko DA, Kurnikov IV, Borisenko GG. Kagan VE, et al. Among authors: zhao q. Nat Chem Biol. 2005 Sep;1(4):223-32. doi: 10.1038/nchembio727. Epub 2005 Aug 14. Nat Chem Biol. 2005. PMID: 16408039
Mass-spectrometric characterization of phospholipids and their primary peroxidation products in rat cortical neurons during staurosporine-induced apoptosis.
Tyurin VA, Tyurina YY, Feng W, Mnuskin A, Jiang J, Tang M, Zhang X, Zhao Q, Kochanek PM, Clark RS, Bayir H, Kagan VE. Tyurin VA, et al. Among authors: zhao q. J Neurochem. 2008 Dec;107(6):1614-33. doi: 10.1111/j.1471-4159.2008.05728.x. Epub 2008 Nov 6. J Neurochem. 2008. PMID: 19014376 Free PMC article.
Peroxidase mechanism of lipid-dependent cross-linking of synuclein with cytochrome C: protection against apoptosis versus delayed oxidative stress in Parkinson disease.
Bayir H, Kapralov AA, Jiang J, Huang Z, Tyurina YY, Tyurin VA, Zhao Q, Belikova NA, Vlasova II, Maeda A, Zhu J, Na HM, Mastroberardino PG, Sparvero LJ, Amoscato AA, Chu CT, Greenamyre JT, Kagan VE. Bayir H, et al. Among authors: zhao q. J Biol Chem. 2009 Jun 5;284(23):15951-69. doi: 10.1074/jbc.M900418200. Epub 2009 Apr 7. J Biol Chem. 2009. PMID: 19351880 Free PMC article.
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