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Page 1
Che-1 affects cell growth by interfering with the recruitment of HDAC1 by Rb.
Bruno T, De Angelis R, De Nicola F, Barbato C, Di Padova M, Corbi N, Libri V, Benassi B, Mattei E, Chersi A, Soddu S, Floridi A, Passananti C, Fanciulli M. Bruno T, et al. Among authors: floridi a. Cancer Cell. 2002 Nov;2(5):387-99. doi: 10.1016/s1535-6108(02)00182-4. Cancer Cell. 2002. PMID: 12450794 Free article.
Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint.
Bruno T, De Nicola F, Iezzi S, Lecis D, D'Angelo C, Di Padova M, Corbi N, Dimiziani L, Zannini L, Jekimovs C, Scarsella M, Porrello A, Chersi A, Crescenzi M, Leonetti C, Khanna KK, Soddu S, Floridi A, Passananti C, Delia D, Fanciulli M. Bruno T, et al. Among authors: floridi a. Cancer Cell. 2006 Dec;10(6):473-86. doi: 10.1016/j.ccr.2006.10.012. Cancer Cell. 2006. PMID: 17157788 Free article.
Che-1: a new effector of checkpoints signaling.
Floridi A, Fanciulli M. Floridi A, et al. Cell Cycle. 2007 Apr 1;6(7):804-6. doi: 10.4161/cc.6.7.4043. Epub 2007 Apr 22. Cell Cycle. 2007. PMID: 17377493 Review.
Che-1 promotes tumor cell survival by sustaining mutant p53 transcription and inhibiting DNA damage response activation.
Bruno T, Desantis A, Bossi G, Di Agostino S, Sorino C, De Nicola F, Iezzi S, Franchitto A, Benassi B, Galanti S, La Rosa F, Floridi A, Bellacosa A, Passananti C, Blandino G, Fanciulli M. Bruno T, et al. Among authors: floridi a. Cancer Cell. 2010 Aug 9;18(2):122-34. doi: 10.1016/j.ccr.2010.05.027. Cancer Cell. 2010. PMID: 20708154 Free article.
Che-1 activates XIAP expression in response to DNA damage.
Bruno T, Iezzi S, De Nicola F, Di Padova M, Desantis A, Scarsella M, Di Certo MG, Leonetti C, Floridi A, Passananti C, Fanciulli M. Bruno T, et al. Among authors: floridi a. Cell Death Differ. 2008 Mar;15(3):515-20. doi: 10.1038/sj.cdd.4402284. Epub 2007 Nov 30. Cell Death Differ. 2008. PMID: 18049476
270 results